Department of Hematology and OncologyVIP中华医学杂志(英文版)Gao SJ, Tan YH, Liu XH, Su L, Yu P, et al. (2014) The percentage of peripheral blood blasts on day 7 of induction chemotherapy predicts response to therapy and survival in patients with acute myeloid leukemia. Chin Med J (Engl...
Cellular DNA content distributions of propidium-iodide-stained bone marrow blasts were determined by flow cytometry (FCM) for 225 untreated children with acute leukemia and were correlated with leukemia cell phenotype and karyotype. Aneu... AT Look,SL Melvin,DL Williams,... - 《Blood》 ...
(upto 50%).31 Similarly, erythroid leukemic conditions display a higher percentage of erythroid blasts.32 A paradoxical observation is the detection of an erythroid burden in the late-stage CML patients.21 The mechanisms of altered expression of miRNA182 in myeloid leukemia remain poorly ...
in RPMI + 10% FBS supplemented with 200 U/ml of granulocyte colony-stimulating factor (G-CSF). G-CSF enables AML blasts to proliferate and prevents spontaneous apoptosis without increasing Bcl-2 expression.29The primary AML cells are then treated with 8 μMof the L-Bcl-2 antisense ...
Although less intense therapies are being used more often in AML, the AML-MDS dichotomy remains, with the presence of ≥ 20% myeloblasts in marrow or peripheral blood generally regarded as defining AML. Consequently, patients with 19% blasts are typically ineligible for AML studies, with ...
Determining the percentage of peripheral blood (PB) and bone marrow (BM) blasts is important for diagnosing and classifying acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). Although most patients with acute leukemia or MDS have a higher percentage of BM blasts than PB blasts, ...
The product of the percentage blasts on the bone marrow aspirate (BMA) and the biopsy cellularity has been termed the absolute blast index aspirate (ABI-aspirate) and is used to measure disease response on day 7 of induction therapy. The authors compared the event-free survival (EFS) in ...
Although less intense therapies are being used more often in AML, the AML-MDS dichotomy remains, with the presence of 鈮 20% myeloblasts in marrow or peripheral blood generally regarded as defining AML. Consequently, patients with 19% blasts are typically ineligible for AML studies, with ...
Day 8 ALC was significantly higher in poor steroid responders (day 8 blasts 1脳109 cells/l) ( p 0.0001). At the EOI, CD4CD8+ cell percentage in peripheral blood were significantly higher in MRD-positive patients than MRD-negative patients ( p =0.01). Our study suggests that ALC at any...
Patnaik MM, Hanson CA, Sulai NH, Hodnefield JM, Knudson RA, Ketterling RP et al. Prognostic irrelevance of ring sideroblast percentage in World Health Organiza- tion-defined myelodysplastic syndromes without excess blasts. Blood 2012; 119: 5674-5677....