Contrary to common belief, ITT analysis was more conservative than PP analysis in the majority of antibiotic non-inferiority trials. The lower treatment success rate in the ITT analysis led to a larger variance and wider CI, resulting in a more conservative lower CI limit. ITT analysis should ...
per protocol 网络 符合方案集; 方案分析;[例句]The primary endpoint was overall survival, and analysis was per protocol.研究的主要目的是比较总生存时间。as treated cohort 翻译为：为处理队列 【附】per 英[pə(r)] 美[pɚ]prep. 由; （表示根据） 依照; （表示比...
Coefficients from Intent-to-Treat (ITT) and Per-Protocol (PP) Analysis of Adherence.Susan A. StonerPamela B. ArenellaChristian S. Hendershot
Assessing per-protocol (PP) treatment efficacy on a time-to-event endpoint is a common objective of randomized clinical trials. The typical analysis uses the same method employed for the intention-to-treat analysis (e.g., standard survival analysis) applied to the subgroup meeting protocol ...
Overall survival (OS) was analyzed according to treatment strategy (NAT versus US) and analytic methods (intention-to-treat analysis (ITT) and per-protocol analysis (PP)). In 14 studies, 2,699 and 6,992 patients were treated with NAT and US, respectively. Although PP analysis showed the ...
AnswersAnswer d would result in a trial participant being included in the per protocol analysis, whereas a, b, c, and e would not.The effectiveness of 4% dimeticone lotion compared with 0.5% phenothrin liquid in treating head louse infestation was invest
Statistical interpretation of data collected in a randomised controlled trial (RCT) is conducted on the intention‐to‐treat (ITT) and/or the per‐protocol (PP) study populations. ITT analysis is a comparison of treatment groups including all patients as originally allocated after randomisation regard...
For superiority trials, the intent-to-treat population (ITT) is considered the primary analysis population because it tends to avoid the over-optimistic estimates of efficacy that results from a per-protocol (PP) population. However, the roles of the ITT population and PP population in non-infer...
符合方案分析 符合方案分析（per-protocol analysis）是2019年全国科学技术名词审定委员会公布的肠外肠内营养学名词。定义 只对依从性好、遵照方案基本完成治疗计划的受试者进行统计分析。即排除严重违背方案者后，评价处理措施效能的分析方法。出处 《肠外肠内营养学名词》第一版 ...