In natural waters the main source of amino acids is the decomposition of proteins. But this process also produces a variety of small peptides as intermediate cleavage products. In the present study we tested whether amino acids actually are the natural and adequate stimuli for the olfactory ...
Amino Acid- vs. Peptide-Odorants: Responses of Individual Olfactory Receptor Neurons in an Aquatic SpeciesmagnetismmonopolesskyrmionsAmino acids are widely used... H Thomas,LP Pallesen,S Detlev,... - 《Plos One》 被引量: 2发表: 2012年 Transduction mechanisms in vertebrate olfactory receptor cells...
Pharmacokinetics of 1-deamino-8-D-arginine vasopressin after various routes of administration in healthy volunteers. Clin. Endocrinol. 38, 177–182 (1993). Reports the oral bioavailability (0.1%) of one of the first oral formulations of the synthetic hormone desmopressin. CAS Google Scholar ...
One solution for this problem is to sample a still larger number of possible macrocyclic conformations to identify those that satisfy both binding and structural criteria. Incorporating non-canonical amino acids with strong torsional preferences and cross-linking chemistries could help stabilize the designe...
The activity of the hypothalamic feeding centers is also responsive to basic nutrients including glucose, amino acids, and fatty acids besides other metabolites, such as ketone bodies. Much like the hypothalamus acting at the organismal level to regulate homeostasis by integrating such hormonal and ...
K Uma,VS Chauhan,A Kumar,... - 《Chemical Biology & Drug Design》 被引量: 150发表: 1988年 Synthesis of dehydroamino acids and peptides by dehydrosulfenylation. Rate enhancement using sulfenic acid trapping agents Trapping agents lower the reaction temperatures by preventing readdition of sulfenic...
In this paper a hypothesis that some special signals (“key-signals” excito-amino acids, β-amyloid peptides and α-synuclein) are not only involved in information handling by the neuronal circuits, but also trigger out substantial structural and/or functional changes in the Central Nervous Syste...
An organometallic 4d transition metal complex [Cp*RhCl2]2, together with commercially available dyes, was used to construct indicator displacement assays (IDAs) for the detection of peptides, amino acids, and nucleotides. The combination of the Cp*Rh complex with the dye azophloxine was found to...
Peptides are small molecules consisting of two or more amino acids. While they degrade quickly in the body, they show promise as guiding molecules for targeted drug delivery, with deep tissue penetration and low toxicity. Byungheon Lee at Kyungpook National University in Daegu, South Korea, and...
The sequence of amino acids in oxytocin, with a proposal for the structure of oxytocin. J. Biol. Chem. 205, 949–957 (1953). CAS Google Scholar Du Vigneaud, V., Ressler, C., Swan, J. M., Roberts, C. W. & Katsoyannis, P. G. The synthesis of oxytocin. J. Am. Chem. Soc....