Peptide as regulators of the immune system: emphasis on somatostatin. Krantic S. Peptides . 2000Krantic S. Peptide as regulators of the immune system: emphasis on somatostatin. Prptides. 2000;21:1941-1964.Peptides as regulators of the immune system: emphasis on somatostatin - Krantic...
Sequences for nine of these were obtained by a combination of automated Edman degradation and tandem mass spectrometry. All of the peptides are derived from secretory or integral membrane proteins that are synthesized by the antigen-presenting cell itself. Peptides were 16 to 18 residues long, ...
Proopiomelanocortin (POMC), the precursor for melanotropic, corticotropic, and opioid peptides such as alpha-melanocyte-stimulating hormone (alpha MSH), AC... E Schauer,T Schwarz,TA Luger - 《Journal of Clinical Investigation》 被引量: 679发表: 1994年 Modulation of the fish immune system by ...
pumilus or self-mt peptide bound to P9/HLA-A2 tetramers, arguing for cross-reactivity between T cells with specificity for self and foreign homologs of the altered mt peptide. These findings provide proof of principal that the immune system can recognize peptides arising from spontaneous somatic ...
Immune modulation by multifaceted cationic host defense (antimicrobial) peptides. Cationic host defense (antimicrobial) peptides were originally studied for their direct antimicrobial activities. They have since been found to exhibit mul... AL Hilchie,K Wuerth,REW Hancock - 《Nature Chemical Biology》...
Antimicrobial peptides play a pivotal role as key effectors of the innate immune system in plants and animals and act as endogenous antibiotics. The molecules exhibit an antimicrobial activity against bacteria, viruses, and eukaryotic pathogens with diff
Activated T cells provide the “engine” for the chronic inflammation that is associated with autoimmune diseases, organ graft rejection and tumor immunity.CD31 (PECAM-1)Immune responses can be controlled by inhibitory immune receptors among which CD31 (PECAM-1), which is expressed exclusively and ...
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Hence, in order to be able to use this class of peptide (retro-D) for vaccine development, they should be coupled to other immunogenic structures to facilitate recognition by the immune system. However, if these peptides are to have applications as other types of therapeutic agent (and an ...
Cationic peptides with an emphasis on their antimicrobial activities; traditional terminology for host defence peptides. Immunomodulatory The ability to modulate the immune response, including by influencing the production of chemokines and cytokines. ...