Martin Conda-Sheridanhttps://ror.org/00thqtb16grid.266813.80000 0001 0666 4105Department of Pharmaceutical SciencesUniversity of Nebraska Medical Center (UNMC) 68198 Omaha NE USASpringer USMedicinal Chemistry Research
Research programme: peptide-based therapeutics - PYC Therapeutics/Johnson & Johnson Research Latest Information Update: 15 Sep 2023 Price :€55* Adis is an information provider.We do not sell or distribute actual drugs. Final gross price and currency may vary according to local VAT and billing ad...
Therapeutic peptides play an essential role in human physiology, treatment paradigms, and bio-pharmacy [1,2,3]. Over the last few decades, peptide-based therapeutics have received a great deal of attention from researchers due to their advantages in drug discovery and design [4,5]. During the...
Antibody targeted drugs as cancer therapeutics. Nat. Rev. Drug Discov. 2006, 5, 147–159. [Google Scholar] [CrossRef] Majumdar, S.; Siahaan, T.J. Peptide-mediated targeted drug delivery. Med. Res. Rev. 2012, 32, 637–658. [Google Scholar] [CrossRef] Zhao, Y.; Ren, W.; Zhong,...
Owing to the various problems associated with chemical entity based drugs, the current focus has been on moving toward peptides as therapeutics and approximately 140 peptide based therapeutics are being evaluated in clinical trials11,12. Peptide based anti-cancer agents have the potential of providing...
We believe that the field of peptide-based therapeutics continues to grow with the application of traditional rational drug designing approach to improve current weakness of peptides in terms of low membrane permeability, ability of aggregation, prone to hydrolysis, and oxidation. We believe that pept...
This substantiates the need for the development of additional, specific therapeutics targeting ErbB2-positive cells. Here we describe the development and testing of a peptide-based immunotoxin, NL1.1-PSA, that exhibits ErbB2-specific cytotoxicity. The utilization of the immunotoxin described here could...
Peptide based therapeutics and their use for the treatment of neurodegenerative and other diseases. Baig, M. H., Ahmad, K., Saeed, M., Alharbi, A. M., Barreto, G. E., Ashraf, G. M., & Choi, I. (2018). Peptide based therapeutics and their use for the treatment of neurodegener...
Cell-penetrating peptides transport therapeutics into cells. Pharmacol. Ther. 2015, 154, 78–86. [CrossRef] [PubMed] 30. Feni, L.; Neundorf, I. The Current Role of Cell-Penetrating Peptides in Cancer Therapy. Adv. Exp. Med. Biol. 2017, 1030, 279–295. [PubMed] 31. Bolhassani, A...
Anticancer peptides (ACPs) perform a promising role in discovering anti-cancer drugs. The growing research on ACPs as therapeutic agent is increasing due to its minimal side effects. However, identifying novel ACPs using wet-lab experiments are generally