Development Trends for Peptide Therapeutics. San Diego, CA: Peptide Therapeutics Foundation (PTF); 2010. This report is a comprehensive assessment of the current status of peptide therapeutics in clinic or under developmentReichert J. Development Trends for Peptide Therapeutics. San Diego, CA: Peptide...
Development trends for peptide therapeutics (Peptide Therapeutics Foundation, 2010). Fosgerau, K. & Hoffmann, T. Peptide therapeutics: current status and future directions. Drug Discov. Today 20, 122–128 (2014). Article PubMed Google Scholar Lau, J. L. & Dunn, M. K. Therapeutic peptides...
Reports derived from an earlier version of this dataset have been published through the Peptide Therapeutics Foundation and elsewhere;15, 16 in the intervening years, we have continued to maintain and curate a proprietary version of the data at Ferring Research Institute. The analysis presented in ...
Herein, we focused on the multifunctional application of peptides in targeted therapeutics; peptides can deliver carriers (such as nanoparticles, extracellular vesicles (EVs), and cells) and cargoes (such as cytotoxic peptides, radioisotopes, and small molecules) to target cells; inhibit or ...
mouse and rat with mouse being the prime target with highest toxicity imparted causing its death by respiratory failure [98]. Pentapharm Ltd. has developed an anti-wrinkle cream SYN-AKE™ which is a peptide mimic of Wtx-1, it is a prime example of waglerins use in therapeutics [99]. ...
Over the last few decades, peptide-based therapeutics have received a great deal of attention from researchers due to their advantages in drug discovery and design [4, 5]. During the epidemic of COVID-19, therapeutic peptides have shown their potential as the agents against SARS-CoV-2 [6,...
This review is an attempt to illustrate the diversity of peptides reported for a potential or an established use in cancer therapy. With 612 references, this work aims at covering the patents and publications up to year 2000 with many inroads in years 2001–2002. The peptides are classed acc...
A key strategy in peptide therapeutics is the development of innovative delivery platforms. In current clinical trials, the OmniPod (Insulet Corporation, Billerica, Massachusetts) insulin delivery system is being used to administer long-term SQ CD-NP in patients with HF. In experimental models of ...
Peptide therapeutics: targeting the undruggable space. Eur. J. Med. Chem. 94, 459–470 (2015). CAS PubMed Google Scholar Kintses, B. et al. Phylogenetic barriers to horizontal transfer of antimicrobial peptide resistance genes in the human gut microbiota. Nat. Microbiol. 4, 447–458 (...
Therefore, peptide therapeutics have the potential to be effective and low-cost cancer treatments. Chemokinostatin-1 (CKS1) is a 24-mer peptide originally discovered as an anti-angiogenic peptide. Karagiannis and Popel developed a computational method to identify anti-angiogenic sequences contained ...