A sufficient amount of drug is delivered to the cancer site while minimizing contact with healthy tissue. In this review, we provide an overview of the overall and each part of PDCs function for therapeutics, summarise the targets, and the way of improving PDC drug bioavailability. We also ...
Nature Methods thanks Abdelghani Oukhaled and the other, anonymous, reviewer(s) for their contribution to the peer review of this work. Primary Handling Editor: Arunima Singh, in collaboration with the Nature Methods team. Additional information Publisher’s note Springer Nature remains neutral with...
NGC system (Bio-Rad) with a reversed-phase column and detected at 280 nm. The concentrations of s-RhTx were calculated by the absorbance at 280 nm wavelength and adjusted using an extinction coefficient 0.662 mM−1cm−1(calculated on the websitehttps://web.expasy.org/protparam)....
Subject: Review ScienceOpen disciplines: Pharmacology & Pharmaceutical medicine Keywords: marine organism,anticancer medicine,small peptide,liner peptide,cyclic peptide Data availability: ScienceOpen disciplines: Pharmacology & Pharmaceutical medicine Keywords: marine organism, anticancer medicine, small peptide...
8 The University of Alabama at Birmingham, University of Vermont, Wake Forest University School of Medicine, University of Arkansas for Medical Sciences, University of Cincinnati, and Indiana University Institutional Review Boards approved the study protocol. A stratified random cohort of 4415 ...
RY, YZ, ZX and WW did the literature review. XJ, ZX, RY and YZ. made the website. SCL proposed the topic, supervised this project and revised the manuscript. All authors read and approved the final manuscript. Corresponding author Correspondence to Shuaicheng Li....
Clark et al., “Engineering stable peptide toxins by means of backbone cyclization: Stablization of the α-conotoxin MII” Proceedings of the National Academy of Sciences, Sep. 27, 2005, 102(39), 13767-13772. Bax, A. et al., “MLEV-17-Based Two-Dimensional Homonuclear Magnetization Tran...
[2 ]Department of Chemistry and Biomolecular Sciences & Biotechnology Research Institute, Macquarie University, Sydney, Australia Article Publisher ID: 1471-2105-6-249 DOI: 10.1186/1471-2105-6-249 PMC ID: 1276010 PubMed ID: 16221310 SO-VID: 0b0d6c8b-60d8-4e54-8ac5-f293ad833590 Copyri...
We acknowledge funding support from Cancer Research UK (CRUK, C5255/A15935), a CRUK grant (C5255/A18085) through the CRUK Oxford Centre, the Medical Research Council (MC_PC_12004) and the Engineering and Physical Sciences Research Council (EPSRC) Oxford Centre for Drug Delivery Devices (EP...
Open AccessReview by Ethan Heh † , Jesse Allen † , Fabiola Ramirez , Daniel Lovasz , Lorena Fernandez , Tanis Hogg , Hannah Riva , Nathan Holland and Jessica Chacon * Paul L. Foster School of Medicine, Department of Medical Education, Texas Tech University Health Sciences Center, El Pa...