Drug delivery: Week-long diabetes therapy A subcutaneous depot of a diabetes drug fused to a thermosensitive biopolymer leads to blood-glucose control, for over one week after a single injection, in animal models of type-2 diabetes. Omid Veiseh News & Views13 Jun 2017 Nature Biomedical Engi...
This chapter focuses on the use of peptides as novel transdermal drug delivery agents. Peptides offer several advantages over traditional methods in delivering drugs due to the ease of design and use, chemical diversity, and potentially low toxicity and immunogenicity. We discuss the potential of ...
[2] Carrasco-Triguero, M. et al. Immunogenicity assays for antibody-drug conjugates: case study with adotrastuzumab emtansine. Bioanalysis. 2013, 5, 1007–1023. [3] Vhora, I. et al. Receptor-targeted drug delivery: current perspect...
Medicilon's Peptide Drug Conjugate (PDC) R&D Service Platform can provide services such as the research and innovative peptide drugs, new peptide dosage forms, and peptide generic drugs.
It consists of ceramic core coated with poly hydroxyl oligomer, on which protein and peptide drug can be adsorbed. Aquasomes preparation, characterization, and application in protein and peptide drug delivery are discussed. Microneedles are promising transdermal approach; it involves creation of micron-...
Peptides are also being developed for improving drug delivery through the intestinal mucosa barrier (IMB) and the blood-brain barrier (BBB). These peptides were derived from intercellular junction proteins such as occludins, claudins, and cadherins and improve drug delivery through the IMB and ...
Peptide-based drug delivery systems have many advantages when compared to synthetic systems in that they have better biocompatibility, biochemical and biophysical properties, lack of toxicity, controlled molecular weight via solid phase synthesis and purification. Lysosomes, solid lipid nanoparticles, dendrime...
opens new potential for exploring the strategy of drug delivery in clinical applications. Keywords: drug delivery;peptide;micelles
His laboratories, focusing on the formulation of biopharmaceutical drugs and vaccines, freeze- and spray-drying as well as micro- and nanoparticle drug delivery, are based at the IBME, where he currently heads the Wolfson Vaccine Delivery Technology Centre. Dr. Schiffter is a registered pharmacist...