ABSORPTION SPECTRUM OF THE PEPTIDE BOND II. INFLUENCE OF CHAIN LENGTHThe absorption spectra of polylysine, n = 6, 14, 33, 48 and 53, and polyornithine, n = 35, are reported. Study of the molar extinction vs. pH curves for hexalysine and triglycine shows that at pH between 1 and 7...
(a) Ion chromatogram representing peptides SM(ox)IRPPY, M(ox)IRPPY and SMIRPPY of individual 1_CM16-5 and 2_CM16-6; the occurrence of these three specific peaks confirms the presence of AMELY; (c) fragmentation spectrum of peptide SM(ox)IRPPY (monoisotopic mass [M + 2 H]+...
MYRbase: analysis of genome-wide glycine myristoylation enlarges the functional spectrum of eukaryotic myristoylated proteins. Genome Biol 2004; 5: R21. 32. Agemy L, Friedmann-Morvinski D, Kotamraju VR, Roth L, Sugahara KN, Girard OM et al. Targeted nanoparticle enhanced proapoptotic peptide ...
Fungal non-ribosomal peptide synthetase (NRPS)-encoding products play a paramount role in new drug discovery. Fusarium, one of the most common filamentous fungi, is well-known for its biosynthetic potential of NRPS-type compounds with diverse structural
Fourier-transformed infrared spectroscopy (FT-IR) identifies a substance by comparison with a reference spectrum [43]. However, within FT-IR measurements, further investigations are necessary for a quantitative statement [87]. This can be done via X-ray photoelectron spectroscopy (XPS) [48] or ...
In contrast to the free state, the NMR spectrum of the bound state shows sharp signals (Fig.4a,bottom), indicating that the exchange process is quenched in the presence of the peptide. The secondary structure is as designed (Fig.4b, red bars, and Extended Data Fig.6c) except for β4,...
Polypeptides absorb IR radiation at specific frequency ranges based on the type of chemical bond (i.e. single vs double), quality of bond vibration (i.e. stretch vs bend), and the mass of the involved nuclei. IR absorbance in the amide I region (1600–1700 cm− 1) is based ...
spectrum of antimicrobial activity, a decreased incidence to induce resistance, and the membrane-targeting mode of action, which made peptides not affected by antibiotic-resistance mechanisms [81]. Whether there are other modes of action for tick defensins remains to be further explored. Nonetheless,...
which could facilitate selenoetherVformation through nucleophilic attack on the carbon center α to the Se-P bond of the activated selanylphosphoniumII+via a hypothetical transition state (TS-IV). This process would lead to the formation of a thermodynamically favourable π-bond between Se and P...
hydroxy acid 6, sfGFP(3BocK-OH)-His6, from a sfGFP-3-TCG gene in Syn61∆3(ev5) cells harbouring the MmPylRS/MmtRNAPylCGA orthogonal pair was confirmed by ESI–MS—only a mass that corresponds to hydroxy acid incorporation followed by ester bond cleavage at position 3 was detected. ...