Peptide Bond Proteins, which are vital to the functionality of all living organisms, are made up of multiple amino acid monomers linked together via peptide bonds. Peptide bonds are chemical covalent bonds linking one amino acid to the other, and they form between a carbon atom of one amino...
hello everyonewelcome to my presentation today i amyoungi'm the lead scientist from chemicaldevelopment department from fairingpharmaceuticals indenmark the title of my presentationtoday is the peptide set reactions anddegradationsand part of the contents from mypresentation today iscited in my book sit...
11. A compound according to claim 1 additionally comprising a resin support linked directly via a peptide bond or indirectly via a linker peptide moiety to the lipophilic anchor section. 12. A compound according to claim 1 having the formula ##STR5## wherein Z, Z1and Z2are independently ...
The novel bradykinin antagonist peptides of the present invention represented by the general formula (I) are ZPA-Arg-Pro-Hyp-Gly-Thia-Ser-D-Tic-Oic-Arg-OH (I) A is Arg, D-Arg, D-Lys or a chemical bond, P is a chemical bond, or a group of the formula -NR2- (U) -CO-, ...
6A. Conversely, the terms with YIJ(1) and YIJ(2) dominate in the interactions between the nucleic-acid-base pair, one base in a pair being purine with dominant parallel and one pyrimidine with dominant perpendicular component; these terms favor the virtual-bond axes making an angle, as ...
Arnaiz B, Madrigal-Estebas L, Todryk S, James TC, Doherty DG, Bond U: A novel method to identify and characterise peptide mimotopes of heat shock protein 70-associated antigens. J Immune Based Ther Vaccines. 2006, 4: 2-10.1186/1476-8518-4-2. Article PubMed Central PubMed Google Schol...
biosynthesis, extending their well-established role in controlling peptide stereochemistry (working in concert with epimerization (E) domains) to gating in trans modifications, recruiting trans-acting enzymes and performing additional chemical transformations of their substrates during peptide bond formation (...
The NP peptide for derivatization according to the present invention is defined by the following formula, where it should be understood that a peptidic bond links Arg18 and Ile19 and the line between Cys11 and Cys27 represents a direct disulfide bridge: X1 is Thr or absent; X2 is Ser, Th...
p-toluenesulfonate or acetate. In the process of the invention, the condensation reaction in which the peptide bond is formed can be conducted in an aqueous solution having a pH which maintains enzyme activity which is about 4 to 7.5 for the thiol proteinase and 6 to 9 for the serine protei...
N-methylation of the peptide bond between Asp and 1Nal seemed most promising in achieving a further improvement in tumor targeting. In line with these results, [111In]In-DOTA-[(N-Me)1Nal8]MGS5 showed the highest improvement in tumor uptake in the A431-CCK2R xenografts (48.10 ± 9.15% ...