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非职业暴露后预防(nPEP)使用抗逆转录病毒药物来预防人类免疫缺陷病毒(HIV)感染,是美国疾病控制与预防中心和世界卫生组织推荐的关键策略之一。nPEP最初是为了预防职业暴露,如针刺伤害,尽管没有随机临床试验数据,但观察性研究表明,nPEP在预防职业和非职业暴露(如无保...
PEP:是尚未感染HIV的人员,在暴露于高感染风险后(如与HIV感染者或感染状态不明者发生体液交换行为)及早(不超过72小时)服用特定的抗病毒药物,降低HIV感染风险的方法4。 PrEP:是处于较高HIV感染风险人群通过服用抗病毒药物来预防HIV感染的一种新型有效的生物医学预防方法,使用人群的HIV检测结果必须呈阴性5(图2)。 (...
In the last several decades, postexposure prophylaxis (PEP) with antiretroviral therapy (ART) has become an effective tool for the prevention of HIV transmission. The continuous evolution of antiretrovirals and the associated update of clinical practice guidelines create a challenge for NPs caring for...
核酸检测(NAT)在存在PrEP的情况下发现早期HIV感染，或与血清学检测相一致。未检测到的HIV RNA将在PrEP...
核酸检测(NAT)在存在PrEP的情况下发现早期HIV感染，或与血清学检测相一致。未检测到的HIV RNA将在PrEP...
Antoine Prestat,PEP-Therapy创始人&CEO。 Antoine Prestat,PEP-Therapy创始人&CEO。 竞品信息 42 导出 序号产品名称当前融资轮次成立日期产品标签所属地简介所属公司 1 溪砾科技 A轮 2021-05-21 医疗健康 广东 ReviR溪砾科技是一家结合AI技术进行靶向RNA小分子药物研发的生物科技公司,针对中枢神经系统疾病、癌症和...
After you finish therapy, you will be tested for HIV, and most doctors will also require three-month and six-month checkups to ensure you are in fact negative. Your doctor should also monitor your liver and kidney function for toxicities during and after treatment. ...
What role, if any, does the rapidHIVantibody test have in a protocol for postexposure treatment of needlestick or other significant exposures to body fluids from HIV-infected patients? Is it worth delaying the initiation of therapy until the results of that test are available?
Chang YS, et al. (2013) Stapled alpha-helical peptide drug development: A potent dual inhibitor of MDM2 and MDMX for p53-dependent cancer therapy. Proc. Natl. Acad. Sci. U. S. A. 110(36):E3445-E3454. Walensky LD & Bird GH (2014) Hydrocarbon-stapled peptides: principles, practice,...