doi:10.1007/978-1-4614-1533-6_41Five-EF-hand calcium-binding proteins; PEF Proteins that possess a domain of five serially repetitive EF-hand-like motifs. Eukaryotes have a group of proteins that possess a domain of five serially...Maki, MasatoshiSpringer New York...
ALG-2, a 22-kDa Ca2+-binding protein, possesses five serially repetitive EF-hand motifs (EF1 to EF5) and belongs to the penta-EF-hand (PEF) family [8]. Previously, we reported that ALG-2 bound Ca2+-dependently to TSG101 at its Pro-rich region [9]. Using lysates of cells exogenous...
Maki, M., Penta-EF-hand (PEF) proteins and calsenilin/DREAM: Involvement of the new EF-hand calcium-binding proteins in apoptosis and signal transduction, this book.Maki M and Penta-EF-Hand (2000) Proteins and Calsenilin/DREAM: Involvement of the New EF-Hand Calcium-Binding Proteins in ...
ALG-2(a gene product of PDCD6) is a 22-kD protein containing five serially repetitive EF-hand structures and belongs to the penta-EF-hand(PEF) family,including the subunits of typical calpains.ALG-2 is the most conserved protein among the PEF family members and its homologs are widely ...
Structures, functions and molecular evolution of the penta-EF-hand Ca2+-binding proteins. Biochem Biophys Acta 2002;1600:51-60.Maki;M;Kitaura;Y;Satoh;H;et;al.Structures,functions and molecu- lar evolution of the penta-EF-hand Ca2+-binding proteins.Biochimica et Biophysica Acta.2002...
penta-EF-hand family.Sorcin is a 198 amino-acid Ca 2+ -binding protein that belongs to the penta-EF-hand family. Its Ca 2+ -binding domain (residues 33–198) has been crystallized in the absence of Ca 2+ in two different crystal forms. Two complete data sets have been collected on ...
We then examine the known roles of Ca2+ in ER proteostasis and trafficking with a particular emphasis on the Inositol 1,4,5-Trisphosphate Receptors (IP3Rs) and the Penta-EF-Hand (PEF) proteins ALG-2 and Peflin. Chapter 2 describes experimental procedures while Chapter 3 examines the roles ...
MELLA M, COLOTTI G, ZAMPARELLI C, VERZILI D, ILARI A, CHIANCONE E (2003) Information transfer in the penta-EF-hand protein sorcin does not operate via the canonical structural/functional pairing: a study with site-specific mutants. J Biol Chem 278:24921- 24928...
It belongs to the penta-EF-hand (PEF) protein family, which contains five EF-hand motifs that associate with membranes in a calcium-dependent manner. Prototypic members of this family are the calcium-binding domains of calpain, such as calpain dVI. Full-length human sorcin has been ...
The penta-EF-hand domain of ALG-2 interacts with amino-terminal domains of both annexin Ⅶ and annexin Ⅺ in a Ca2+-dependent manner. Satoh H,Nakano Y,Shibata H, et al. Biochimica et Biophysica Acta . 2002Satoh, H., Nakano, Y., Shibata, H., and Maki, M., The penta-EF-hand ...