pem-seq原理 PEM-seq(Parallel-epitope motif sequencing)即平行表位基序测序, 是一种用于在全基因组范围内系统性鉴定蛋白质与DNA相互作用序列的技术,可深入解析蛋白质的DNA结合特异性,原理如下: 1. 构建随机DNA文库。 合成包含大量随机DNA序列的文库,这些序列长度通常在几十到上百碱基对不等,涵盖了各种可能的DNA...
pem-seq 原理pem-seq Pem-seq, short for Protein Engineering by Multiscale Sequence Evolution, is a novel method in the field of protein engineering. It aims to predict the effects of mutations on protein function and stability, enabling the design of proteins with desiredproperties. This ...