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Google Share on Facebook pegademase [peg-ad´ĕ-mās] adenosinedeaminasederived from bovine intestine and attached covalently topolyethylene glycol, used in replacement therapy for adenosine deaminase deficiency in immunocompromised patients. Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing,...
药品名称:ADAGEN,活性成分:PEGADEMASE BOVINE,剂型:INJECTABLE;INJECTION,规格:250 UNITS/ML,药品注册申请号:019818,产品号:001
网络释义 1. 酶类药 是一种酶类药(含pegademase bovine)相关词: adaga adage Adagel adagent adagiare adagiarsi adagietto adagiettos adagio ad… zh-cn.oldict.com|基于 1 个网页
elapegademaseenzyme replacement therapypegademasesevere combined immunodeficiencySummary The absence of adenosine deaminase (ADA) causes severe combined immune deficiency (SCID), which has been treated with PEGylated bovine‐extracted ADA (ADAGEN). ADAGEN was recently replaced by a PEGylated recombinant ...
B.Max Units (per dose and over time) [HCPCS Unit]:•23 mg twice weekly III.Initial Approval Criteria Coverage is provided in the following conditions:Universal Criteria 1 •Must not be used in combination with pegademase-bovine; AND •Patient does not have severe thrombocytopenia (<50,...
Beginning in 1990, ERT was performed with PEGylated bovine intestinal ADA (ADAGEN (R)). In 2019, a PEGylated recombinant bovine ADA (Revcovi (R)) replaced ADAGEN following studies in older patients previously treated with ADAGEN for many years. There are limited longitudinal data on ERT-na & ...
III.Initial Approval Criteria Coverage is provided in the following conditions: Universal Criteria 1 • Will not be used in combination with pegademase-bovine; AND • Patient does not have severe thrombocytopenia (i.e., platelet count <50,000/microL); AND Adenosine Deaminase (ADA) ...