(PEO)blockswereintroducedintothepolyesterbyusingcopolymcrizafion.AmphiphilicdiblockeopolymerofPCL-PEGhasbeensynthesized.Polymermicrosphereshavebeenpreparedandtheirenzymaticdegradationbehaviorhavebeeninvestigated.Inthisworkaseriesofamino-termina唧PEGhomopolymcrwithdifferentmolecularweight2000,3000,4000weresynthesizedbyanionic...
JanaDepartmentPrabalDepartmentKumarDepartmentMannaDepartmentGuruDepartmentPrasadDepartmentSpringerProgress in BiomaterialsMohanty, A.K., Jana, U., Manna, P.K., Mohanta, G.P., 2015. Synthesis and evaluation of MePEG-PCL diblock copolymers: surface properties and controlled release behavior. Prog. Biomater...
HO-PEG-PCL, a hydroxyl polyethylene glycol polycaprolactone diblock copolymer, is a highly biocompatible and biodegradable polymer material. The synthesis method of HO-PEG-PCL generally adopts the method of first preparing PCL and then block copolymerizing it with HO-PEG. Specifically, PCL is first ...
PEG-PCL 共聚物纳米粒降解行为及其用作药物载体的 研究 摘要 脂肪族聚酯,如聚己内酯(PCL)、聚丙交酯(PLA)、聚乙交酯(PGA) 等在医药方面具有广泛的用途,近年来引起人们的注意。由生物相容 性和可降解性的两亲性共聚物(如PEG-PCL,PCL-PEG,PCL-PLA-PEG) 自组装形成的纳米粒子(胶束),近年来在药物输送系统成为一...
HO-PEG-PCL, a hydroxyl polyethylene glycol polycaprolactone diblock copolymer, is a highly biocompatible and biodegradable polymer material. The synthesis method of HO-PEG-PCL generally adopts the method of first preparing PCL and then block copolymerizing it with HO-PEG. Specifically, PCL is first...
(diblock and triblock) and star-shaped (three-armed and four- armed) poly[(ethylene glycol)-block-(ε-caprolactone)] copolymers (PEG–PCL copolymers) were synthesized by ring-opening polymerization of ε-caprolactone (CL) with stannous octoate as a catalyst, in the presence of monomethoxypoly(...
ln addition to our full line of Polycaprolactone Diblock and Triblock Polymers, Polysciences, Inc. offers custom synthesis services for other compositions and block molecular weights. The numbers listed under the product indicate the approximate molecular weight of the block segments. The PEG terminal ...
The critical micelle concentration was determined to be 0.4–1.2 mg/l by fluorescence technique using pyrene as probe, depending on the length of PCL blocks, and lower than that of corresponding PCL–PEG diblock copolymers. The 1H NMR spectrum of the micelles in D 2O demonstrated only the –...
fluorescence technique using pyrene as probe,depending on the length of PCL blocks,and lower than that of corresponding PCL-PEG diblock copolymers.The ~1H NMR spectrum of the micelles in D_2O demonstrated only the -CH_2CH_2O-signal and thus confirmed the PCL-core/PEG-shell structure of the...
HO-PEG-PCL, a hydroxyl polyethylene glycol polycaprolactone diblock copolymer, is a highly biocompatible and biodegradable polymer material. The synthesis method of HO-PEG-PCL generally adopts the method of first preparing PCL and then block copolymerizing it with HO-PEG. Specifically, PCL is first...