Illuminating endosomal escape of polymorphic lipid nanoparticles that boost mRNA delivery. Biomater. Sci. 9, 4289–4300 (2021). Article CAS PubMed PubMed Central Google Scholar Madisen, L. et al. A robust and high-throughput Cre reporting and characterization system for the whole mouse brain....
nanoparticlesphoton correlation spectroscopyIn this study, poly ethylene glycol 100 stearate (PEG 100-S) was used to prepare coated solid lipid nanoparticles with loading levothyroxine sodium (levo-loaded PEG 100-S-coated SLNs) by microemulsification technique. Evaluation of the release kinetic of ...
Lipid nanoparticles (LNPs) represent the most clinically advanced mRNA delivery system with two marketed products, i.e., the COVID-19 mRNA vaccines Comirnaty® and Spikevax® from Pfizer/BioNTech and Moderna, respectively. In general, the LNPs used for mRNA delivery typically include four com...
Our lipid nanoparticle development capabilities include liposomes, solid lipid nanoparticles, nanostructured lipid carriers, targeting liposomes, stealth liposomes, etc.Our PEG & Lipid Products High quality and diverse PEG derivatives, PEG copolymers, PEG raw materials and lipid products to meet your diff...
Fig. 1: Design and characterization of nanoparticles for STING agonist delivery. a, Chemical structures of the parent CDN STING agonist (1), CDN prodrug (2), diacyl lipid (3) and CDN-PEG-lipid (4).b, Schematic of LND containing CDN-PEG-lipid.c, Negative stain transmission electron microgr...
Effect of polyethyl- eneglycol (PEG) chain length on the bio-nano-interactions between PEGylated lipid nanoparticles and biological fluids: from nanostructure to uptake in cancer cells. Nanoscale. 2014;6(5):2782-2792.Pozzi D, Colapicchioni V, Caracciolo G, Piovesana S, Capriotti AL, Palchetti...
Enteric-coated capsules filled with mono-disperse micro-particles containing PLGA-lipid-PEG nanoparticles for oral delivery of insulin 文档格式: .pdf 文档大小: 2.46M 文档页数: 11页 顶/踩数: 0/0 收藏人数: 0 评论次数: 0 文档热度: 文档分类: ...
To develop a tumor-targeted drug delivery system based on solid lipid nanoparticles (SLNs) conjugated with the enzymatically cleavable polyethylene glycol (PEG).SLNs loaded with paclitaxel (PTX) were prepared using the film ultrasonication method, followed by conjugation with a PEGylated peptide (Pp)...
The imbalance of the immune system can lead to the occurrence of autoimmune diseases. Controlling and regulating the proliferation and function of effector T (Teff) cells and regulatory T (Treg) cells becomes the key to treating these diseases. Dendritic cells (DCs), as dedicated antigen-presentin...
peptides or other ligands to the surface of liposome and other lipid PEG nanoparticles. Pegylated phospholipids have longer blood circulation time and higher stability for encapsulated drugs. Ponsure has developed a comprehensive collection of thiol reactive maleimide phospholipid PEG products that have hig...