Multidimensional protein fractionation and mass spectrometric analysis of SRNS urine samples combined with immunodepletion identified the 11,117.4 protein as beta2-microglobulin (B2M). Using an unbiased protein profiling approach, we have validated previously reported findings of B2M as a biomarker ...
Product NamePediatric Urine Sample - Ages 14 - 17 Years Old SourceSingle Human Donor Catalogue Number991-03-PED4 PurityRaw Urine FormLiquid Sample Size1 donor x>30 mL Note: Each sample would be from a unique donor. Donor AgeReported
Albumin-bound non-esterified fatty acids can be taken up from the luminal side using fatty acid transport protein 2 (FATP2) [31]. Uptake of fatty acids from the urine is especially relevant in proteinuric kidney disease when high amounts of albumin-bound fatty acids are excreted. In prior ...
Urine protein quantification (preferably first-morning urine protein-to-creatinine ratio) Serum albumin measurement Lipid panel The following tests should be performed in selected patients to determine whether the nephrotic syndrome is primary and idiopathic (INS) or secondary and, if INS has been ...
Protein expression was further validated with Western blot analysis and immunohistochemical assays using CSF, brain tissue, serum, and urine from DIPG and control specimens. Immunohistochemical staining showed selective upregulation of secreted but not cytosolic CypA and DDAH1 in patients with DIPG. In ...
摘要: To address the issue of the scarcity of pediatric nephrologists in developing countries, the International Pediatric Nephrology Association (IPNA) has recognized the need for customize ...关键词: Cardiovascular disease Fetuin-A Matrix Gla protein Phosphorus Vascular calcifications Vascular smooth ...
METHODS: We studied healthy children aged 1 month to 8 years and healthy term and preterm babies; in the last group we only included babies without hemodynamic repercussion. We collected isolated urine samples once for children above 1 month and periodically for those below this age. In this ...
Urine concentrations of two high molecular weight proteins, albumin and IgG, and two low molecular weight proteins, α1-microglobulin (A1M) and retinol-binding protein (RBP), were measured in 657 healthy children from birth to 18 years of age. The urinary levels of RBP and A1M suggest an ...
in the urine), (3) vitamin and mineral supplementation (as increased vitamin C consumption and its subsequent metabolism would increase oxalate levels), and (4) special diets (as increasing protein consumption in the ketogenic or paleo diet results in increased acid loads which downregulates calcium...
These short, non-protein coding RNA molecules are present and stable in tissue, blood, saliva, and urine, making them ideal disease biomarkers. The simple structure of miRNAs and their ability to directly modulate the expression of specific genes lends exciting therapeutic potential to miRNA-based ...