and insurance requirements in NC make her a great addition to our office team. Pat spends most of her free time with the joys of her life, three young grandchildren here in Raleigh ages 6, 9 and10 and two in San Jose, California ages 4 and 6 and her wonderful adult children and ...
anti-TNF or anti-IL1 therapy may indicate that the disease process in such patients may not be refractory to therapy but in fact is driven by a different cytokine, in this case IL6. We conclude that when faced with a JIA patient with apparent resistance to treatment...
This compensatory response may secondarily become harmful as most immune functions are compromised, and thus sepsis-induced immune alterations may play a major role in the decreased resistance to secondary acquired infections in patients who initially survive [3]. This immunosuppressive state is ...
Human milk contains extracellular vesicles (EVs) that carry bioactive molecules such as microRNA, to the newborn intestine. The downstream effects of EV cargo on signaling and immune modulation may shield neonates against inflammatory diseases, including
(Beck Popovic); Hospital Nacional de Niños Dr Carlos Sáenz Herrera, San Jose, Costa Rica (Benavides); Department of Pediatric Oncology, University Hassan II Fès, Fez, Morocco (Benmiloud); Center Hospitalier et Universitaire Ibn Rochd, Casablanca, Morocco (Bennani Guebessi, El Kettani); ...
Sanjad SA, al-Abbad A, al-Shorafa S (1997) Management of hyperlipidemia in children with refractory nephrotic syndrome: the effect of statin therapy. J Pediatr 130(3):470–474 Article CAS PubMed Google Scholar Kano K, Hoshi E, Ito S, Kyo K, Yamada Y, Ando T, Arisaka O, Tomita ...
REH (ATCC) is a pediatric ALL cell line from a patient with recurrent disease Corp., St Louis, MO, USA), (Ser 15) phospho-p53 (Cell Signaling), p53 (Santa Cruz, Biotechnology, Inc., Santa Cruz, CA, USA) and ABL (BD Biosciences, San Jose, CA, USA) in Aquablock/0.1% Tween-20...
Two-Way Analysis of Variance (ANOVA) followed by the Holm-Sidak post-hoc test was used to analyze the response and time-dependent changes in inflammatory mediators across PALF sub-groups and in the mouse HC experiments using SigmaPlot (Systat Software, San Jose, CA) as indicated. ...
syndrome and high-dose steroids (including pulses) used as first-line therapy were not efficacious in ~ 85% [9]. Still, if there was a partial remission seen with conventional oral prednisolone therapy, it appears to be worth trying intravenous methylprednisolone pulses as combination therapy. ...
and use of minimal residual disease to monitor response to therapy2. However, in the past decade outcome has plateaued and remain unacceptably low for many subtypes. Provided that significant improvements in long-term outcome are not expected with conventional therapy alone, therapeutic strategies that...