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Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, MD, George Washington University School of Medicine and Health Sciences, Washington, DC, USAJohn Wiley & Sons, LtdSnyder KM, Donoghue M, Helms WS, Reaman G. Chapter 35: development of drugs for pediatric...
At this age, physical inactivity and sedentary behaviors are significant contributors to the development of pediatric obesity and increase the cardiometabolic risk. Both inactivity and body fat excess significantly impair several components of the health related physical fitness, such as aerobic and muscula...
Glucose intolerance but not an increase in fasting blood glucose levels was observed in growth-restricted rats at 6 mo of age or prior to the development of increased total fat mass and estrous acyclicity. However, fasting blood glucose levels in growth-restricted rats were increased at 12 mo ...
George Washington University Medical Center Thus, biochemical, pharmacological, and histochem- and Children's Hospital of the District of Co- ical techniques describe differential development of lumbia, Washington, D.C. parasympathetic and sympathetic innervation in the One hundred thirty-seven aortas ...
Obesity (Silver Spring). 2010;18(1):190–5. Article PubMed Google Scholar Brown CT, Davis-Richardson AG, Giongo A, Gano KA, Crabb DB, Mukherjee N, et al. Gut microbiome metagenomics analysis suggests a functional model for the development of autoimmunity for type 1 diabetes. PLoS One. ...
Still, Japan’s Pharmaceuticals and Medical Devices Agency (PMDA) has been working to promote pediatric drug development for the nation’s children. Pharmaceuticals and Medical Devices Agency The PMDA’s purpose is to ensure the timely and appropriate review of new drug applications and to promote ...
CDC growth charts for the United States: Methods and development. Vital Health Statistics. Series 11. Vol 246. National Center for Health Statistics; 2002:1-90. 23. Grossman DC, Bibbins-Domingo K, Curry SJ, et al; US Preventive Services Task Force. Screening for obesity in ch...
Center for Drug Evaluation and Research Office of New Drugs Division of Nonprescription Regulation Development, United States Food and Drug Administration, Silver Spring, MD, USA Mona Khurana Center for Devices and Radiological Health, Division of Reproductive, Gastro-Renal and Urological Devices, Renal...
Advances in the miniaturization of sensors and other technologies provide opportunities to collect physiological and/or functional data directly from patie