Here, we show that procollagen C-proteinase enhancer-2 (PCPE-2), a protein previously reported to bind fibrillar collagens and to promote their BTP-dependent maturation, is primarily a potent and specific inhibitor of BTPs which can counteract their proteolytic activities through direct binding. ...
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Using pull-down experiments and an ELISA type binding assay we show here that PCPE-1 binds to three cell membrane HSPGs, syndecans-1, -2 and -4. We also demonstrate that this binding is mediated by the NTR domain and depends on the glycosaminoglycan chains of the syndecans. Using co-...
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(BTMC-A466-1PE)Dectin-1, Human A R-Phycoerythrin (RPE)-conjugated monoclonal mouse antibody, supplied by Biotrend. Supplier Biotrend Host Mouse Clonality Monoclonal (GE2) Conjugate R-Phycoerythrin (RPE) View Product On Supplier's Website ...
Abb. 12.2 Patientin am 40. Tag nach der letzten Menstruation mit einer vaginalen Schmierblutung. Die Sonographie zeigt ein unauffäl- liges rechtes Ovar, das ein Corpus luteum (CL) enthält. Neben dem Ovar ist ein extrauteriner Gestationssack mit einem normal erschei- nenden Dotter...
They can also process the C-terminus of the α1 and α2 chains of procollagens V and XI, although SPCs might act before on the α1 chains. Finally, BTPs mature the N-terminus of the α1 chain of procollagens V and XI but this proteolytic event preserves a large part of their N...