info@scipeptide.com PE 22-28是一种有效的TREK-1抑制剂,其IC50值为0.12 nM。这种药物也是一种由7个氨基酸组成的肽,可以作为制备类似物的核心序列,通过化学修饰和氨基酸取代来实现。PE 22-28在抑郁症的研究中有广泛的应用前景。 PE 22-28作为一种TREK-1抑制剂,具有非常低的IC50值,这意味着它可以有效地抑制TR...
PE-22-28 Function PE-22-28 is a synthetic derivative of the naturally occurring peptide spadin which binds to TREK-1. TREK-1 is found in regions of the brain controlling mood, memory, and learning. Package 10 mg per vial,10 vials per box ...
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Housekeeping tasks such as ergosterol biosynthesis, meiotic spore-wall biogenesis, and n-alkane and fatty acids hydroxylation are examples of primary fungal metabolism [27,28]. The involvement of several fungal P450s in the biosynthesis of secondary metabolites, polyketides, non-ribosomal peptides, ...
Hirose M,Furukawa Y,Kurogouchi F, et al.C-type natriuretic peptide increases myocardial contractility and sinus rate mediated by guanylylcylcase-linked natriuretic peptide receptors in isolated, blood-perfused dog heart preparations. J Pharmacol Experiment Therapy . 1998...
H2-Ab1 plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain contains 6 exons. Exon one encodes the leader peptide, ...
PEX5 is the import receptor, which binds peroxisomal transport signal 1 (PTS1) peptide motifs of the matrix proteins. The cargo-loaded PEX5 is then recruited to peroxisomes with the aid of the peroxisomal membrane proteins PEX13 and PEX14 [[1], [2], [3], [4], [5]]. Trypanosoma ...
Previous studies reported inhibition of STAT3 signaling by RNA interference (RNAi), peptides, and small molecular inhibitors lead to successful suppression of tumor cell growth and metastasis.31 In addition, series of down- stream target genes of STAT3 signaling have been identified, including that ...