近日,来自澳大利亚的 Lowy Cancer Research Centre的John E. Pimanda和Vashe Chandrakanthan研究组在Nature Cell Biology上发表题为Mesoderm-Derived PDGFRA+ Cells Regulate the Emergence of Hematopoietic Stem Cells in the Dorsal Aorta...
These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies ...
2024年2月29日,四川大学李中瀚教授研究团队在Stem Cell Reports上发表题为“MSX1+PDGFRAlow limb mesenchyme-like cells as an efficient stem cell source for human cartilage regeneration”的研究论文。该研究为获取可用于软骨组织修复...
Mesoderm-derived PDGFRA+ cells regulate the emergence of hematopoietic stem cells in the dorsal aortaMouse haematopoietic stem cells (HSCs) first emerge at embryonic day 10.5 (E10.5), on the ventral surface of the dorsal aorta, by endothelial-to-haematopoietic transition. We investigated whether ...
PDGFRa þ cells represent a cell population distinct from CD56 þ myogenic cells, and adipogenic and fibrogenic potentials were highly enriched in the PDGFRa þ population. Activation of PDGFRa stimulates proliferation of PDGFRa þ cells through PI3K-Akt and MEK2-MAPK signaling pathways, and ...
货号25-1401-82 CNY3,331.00 有货 查看价格 批量或定制请求 Application Created with Sketch. 图:1/61 CD140a (PDGFRA) Antibody (25-1401-82) in Flow Staining of NIH/3T3 cells with 0.06 µg of Rat IgG2a K Isotype Control PE-Cyanine7 (Product # 25-4321-82) (blue histogram) or 0.06 ...
PDGFRA is a cell surface receptor tyrosine kinase which binds members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodim...
Human PDGFRA transfected NIH/3T3 cells。 来源宿主 小鼠 反应性 人 保存建议 置于4度避光保存,避免长期暴露在光线下。 避免冻存。 其他 作为全世界最大的单克隆抗体和蛋白生产商,Abnova的金牌品质使其成为全球最主要抗体品牌的供应商,您可以在各个主要抗体品牌,如Abcam、 Sigma、Novus、AbD等知名品牌的目录上都能...
but other cell lines containing these mutations have been shown to be resistant as well. Exogenous expression of the A842V mutation resulted in constitutive tyrosine phosphorylation of PDGFRA in the absence of ligand in 293T cells and cytokine-independent proliferation of the IL-3-dependent Ba/F3...
来源:Human Cells 纯度:Greater than 95% as determined by reducing SDS-PAGE. 内毒素水平:Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test. 形态:Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. 溶解方法:Always centrifuge tubes before opening. Do not mix by vortex ...