磷酸二酯酶(PDE)抑制剂对于女性性功能障碍中的作用.pdf,中国男科学杂志 2008年第22卷第 10期 5 ll ShaJ.ZhouZ.LiJ,eta1.Identification Oftestis BiolReprod2003,68(1):190—8. developmentandspermato--genesis--relatedgenesin 15 ZhouZ,RenX,HuangX,eta1.SM
Opin.Ther.Patents(2007)17(2):147‑ 158)。PDE10A在脑和睾丸中具有有限但高的表达。PDE10独特的在脑(特别是纹状体神经元) 中的高表达表明其抑制剂可能非常适合于治疗神经和精神病症和病况。 [0005]PDE10的抑制被认为可用于治疗精神分裂症和将受益于神经元内cAMP和/或cGMP 水平增加的多种病况或病症,包括多...
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关键词:离散PDE;联合细分;光顺中图分类号:TP3917 文献标识码:A 文章编号:1001-0505(2007)01003505ApplicationofdiscretePDEfairingmethodtocombinedsubdivisionsurfaceHeGangLiaoWenheLiuHao(CollegeofMechanicalandElectricalEngineering,NanjingUniversityofAeronauticsandAstronautics,Nanjing210016,China)Abstract:Discretepartial...
PLoS One 2, e1032 (2007) . Article ADS Google Scholar Yoshida, H., Jono, H., Kai, H. & Li, J. D. . The tumor suppressor cylindromatosis (CYLD) acts as a negative regulator for toll-like receptor 2 signaling via negative cross-talk with TRAF6 AND TRAF7. J. Biol. Chem. 280...
打不开,PDF文件是不能让人编辑的,WPS2007是可以编辑的.
We used Ovid and PubMed (updated April 2007) to conduct an electronic literature search on Medline that included peer-reviewed English-language studies of phosphodiesterase type 5 inhibitor use for either the recovery of erectile function or the treatment of postoperative erectile dysfunction in patient...
European Respiratory JournalJan 2007,29(1)220-221;DOI:10.1183/09031936.00110006 Share This Article: Full Text (PDF) Jump To Article References Figures & Data Info & Metrics PDF Tweet Widget Facebook Like Google Plus One More in this TOC Section ...
[0243] 对PDE7和PDE1B的双重抑制可以为运动障碍的治疗带来另外的好处,其根据是有 报道指出,小鼠中PDE1B基因的删除刺激了多巴胺的代谢并使该动物对多巴胺能激动剂的 作用敏感(Siuciak等人,Neuropharmacology 53(1):113-23(2007))。 [0244] 在一些实施方案中,PDE7抑制剂抑制PDE10活性的IC 要比抑制PDE7A活性的...
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