加拿大约克大学(York University)的Michael G. Organ教授带领的研究团队设计一个结构合理的新催化剂——Pd-PEPPSI-IHeptCl,能够有效地催化仲烷基试剂与各种常见的呋喃、噻吩以及苯丙稠环衍生物(如吲哚、苯并呋喃)发生选择性的交叉偶联反应,大多数情况下收率较高,只有少量的重排产物。 该研究成果作为封面文章发表于《Ang...
Supported byA Journal ofAccepted ArticleTitle: Pd-PEPPSI-IHeptCl: A General Purpose, Highly Reactive Catalyst for the Se-lective Coupling of Secondary Alkyl OrganozincsAuthors: Michael G Organ; Bruce Atwater; Michael Rodriguez; Nalin Chandrasoma;David MitchellThis manuscript has been accepted after p...
Dichloro[1,3-bis(2,6-di-4-heptylphenyl)imidazol-2-ylidene](3-chloropyridyl)palladium(II) (Pd-PEPPSI-IHeptCl), a new, very bulky yet flexible Pd–N-heterocyclic carbene (NHC) complex has been evaluated in the cross-coupling of secondary alkylzinc reactants with a wide variety of oxidativ...
In this report, a new, rationally designed catalyst, Pd-PEPPSI-IHeptCl, is demonstrated to be effective in selective cross-coupling reactions with secondary alkyl reagents across an impressive variety of furans, thiophenes, and benzo-fused derivatives (e.g., indoles, benzofurans), in most ...
Pd-PEPPSI-IHeptCl:用于仲烷基有机锌选择性偶联的通用,高反应活性催化剂 二氯[1,3-双(2,6-二-4-庚基苯基)咪唑-2-基](3-氯吡啶基)钯(II)(Pd-PEPPSI-IHept Cl),一种新的,非常笨重而灵活的Pd -N-杂环卡宾(NHC)络合物已经在烷基仲锌反应物与各种氧化加成伙伴的交叉偶联中得到了高收率和出色的选择性...
In this report, a new, rationally designed catalyst, Pd-PEPPSI-IHeptCl, is demonstrated to be effective in selective cross-coupling reactions with secondary alkyl reagents across an impressive variety of furans, thiophenes, and benzo-fused derivatives (e.g., indoles, benzofurans), in most ...
加拿大约克大学(York University)的Michael G. Organ教授带领的研究团队设计一个结构合理的新催化剂——Pd-PEPPSI-IHeptCl,能够有效地催化仲烷基试剂与各种常见的呋喃、噻吩以及苯丙稠环衍生物(如吲哚、苯并呋喃)发生选择性的交叉偶联反应,大多数情况下收率较高,只有少量的重排产物。