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Abstract As a very promising immunotherapy, PD-1/PD-L1 blockade has revolutionized the treatment of a variety of tumor types, resulting in significant clinical efficacy and lasting responses. However, these therapies do not work for a large proportion of patients initially, which is called primary ...
We thank April Lamb and Jennifer Tepper for clinical operations; Marc Wolfgang, Scott White, Stephen Crimlisk, and Yeimy Garcia for technical operations; Jonathan McGee, Brian Sullivan, Daniel Kallin, Jeff Zhang, Amanda Aldous, and Robyn Eisert for peptide synthesis and manufacturing process ...
Representative images were selected for training using Phenochart (Akoya Biosciences), and an algorithm was created using the inForm Image Analysis software (Akoya Biosciences). Multispectral images were unmixed using the spectral library in inForm software, and tumor tissue was segmented according to ...