These tumor-bearing mice were sacrificed at 24 h after injection and major organs (heart, lung, spleen, liver, and kidney) and tumors were harvested for ex vivo imaging at 640 nm excitation and 680 nm emission. 2.11. Anti-tumor therapy in vivo To establish a subcutaneous 4T1-bearing mice...
Although pyroptosis is critical for macrophages against pathogen infection, its role and mechanism in cancer cells remains unclear. PD-L1 has been detected in the nucleus, with unknown function. Here we show that PD-L1 switches TNFα-induced apoptosis to
It should be noted that the gas exposure setting was set based on the response of Pt/SnO2 sensor, which gave sufficiently stable resistance before exposure to hydrogen, and the same setting was applied to other SnO2 based sensors for direct comparison. For Pd/SnO2 sensor, the base line ...
680 g of S-(-)-5-((2-acetyloxy)-1-oxopropyl)amino)-2, 4, 6-triiodo-1, 3-benzendicarboxylic acid dichloride (prepared as described in WO 96/37460) are dissolved in 1360 g of dimethylacetamide at room temperature and after cooling at 15°C [Solution A ]. 181 g of 2-ammino-1, ...