6.Zhang J, Huang Y, Xi G, Zhang F. HX008: a humanized PD-1 blocking antibody with potent antitumor activity and superior pharmacologic properties. MAbs. 2020;12(1):1724751. 7.Liu R, Li W, Meng Y, Gao S, Zhang J, Hu X. Phase I study of pucotenlimab (HX008), an anti-PD-1...
6.Zhang J, Huang Y, Xi G, Zhang F. HX008: a humanized PD-1 blocking antibody with potent antitumor activity and superior pharmacologic properties. MAbs. 2020;12(1):1724751. 7.Liu R, Li W, Meng Y, Gao S,...
Atezolizumab: A PD-L1-blocking antibody for bladder cancer. Clin Cancer Res 2017;23:1886-90.Inman BA, Longo TA, Ramalingam S, Harrison MR (2016) Atezolizumab: A PD-L1 blocking antibody for bladder cancer. Clin Cancer Res.Inman BA, Longo TA, Ramalingam S, Harrison MR ...
[3] Brant A. Inman, Thomas A. Longo, Sundhar Ramalingam, Michael R. Harrison; Atezolizumab: A PD-L1–Blocking Antibody for Bladder Cancer. Clin Cancer Res 15 April 2017; 23 (8): 1886–1890.
Atezolizumab: A PD-L1-Blocking Antibody for Bladder Cancer. Atezolizumab (Tecentriq, MPDL3280A) is an Fc纬R-binding deficient, fully humanized, IgG1 monoclonal antibody designed to interfere with the binding of PD-L1 ligand to its two receptors, PD-1 and B7.1. By blocking the PD-L1/PD-...
PD1 / PDCD1 / CD279 Blocking Antibody: 别称 Anti-CD279 Antibody; Anti-hPD-1 Antibody; Anti-hPD-l Antibody; Anti-hSLE1 Antibody; Anti-PD-1 Antibody; Anti-PD1 Antibody; Anti-SLEB2 Antibody PD-1 背景信息 Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprote...
In contrast to the RMP1-30 antibody, The 29F.1A12 PD-1 blocking antibody inhibits PD-1 interactions with PD-L1 on live B16-F10 melanoma cells. The RMP1-14 clone, but not 29F.1A12 or RMP1-30, is useful for pulling down (IP) and sequencing PD-1 from B16-F10 and T-cell ...
γδ T cells have the unique ability to detect a wide range of tumors with low mutation burdens, making them attractive candidates for CAR-T-cell therapy. Unlike αβ T cells and other immune cells, γδ T cells are superior in MHC non-restriction, selec
(SASP). Single-cell analysis of p16+cells in vivo revealed that PD-L1 expression correlated with higher levels of SASP. Consistent with this, administration of programmed cell death protein 1 (PD-1) antibody to naturally ageing mice or a mouse model with normal livers or induced nonalcoholic ...
Glioma treatment using a PD-1/PD-L1 blocking antibody Combination therapy strategy and preclinical research The blockade of PD-1/PD-L1 can elicit effective anti-tumor T cell responses. In the past 5 years, the targeting of the PD-1/PD-L1 axis has been at the forefront of immunotherapy due...