The objective of this study was to estimate the annual population-level impact of PCV13 NIPs on vaccine-type and non-vaccine type (NVT) IPD incidence among children and adults using national surveillance data of countries that switched from PCV7 to PCV13 in their NIP. A 20-valent vaccine (...
In this study, we aimed to investigate the pneumococcal lineages behind the predominant serotypes, the mechanism of serotype replacement in disease, as well as the major pneumococcal lineages contributing to invasive pneumococcal disease in the post-vaccine era and their antibiotic resistant traits. ...
However, many of these surveillance sites are still able to serve local purposes, such as serving as sentinels to identify pockets of vaccine-type disease where immunization uptake may be suboptimal. Eligible sites from LMICs that participated Microorganisms 2021, 9, 742 20 of 28 in PSERENADE ...
Non-vaccine serotypes (NVTs) have emerged in countries where PCV vaccination has been introduced [15,19,20,26,27]. It is likely that NVTs were present prior to PCV introduction and have expanded to fill the niches vacated by VTs due to vaccine-induced selective pressure [27]. It is, the...