The present invention describes a process for the preparation of an antigen composition, which antigen composition can be used to prepare a ready-to-use vaccine for swine, for preve
Conclusion Our data demonstrate that Tween-20 transiently changes the surface morphology of PK-15 cells and improves PCV2 infection. The findings of the present study may be utilized in the development of a PCV2 vaccine.Background Porcine circovirus 2 (PCV2), which belongs to family Circoviridae...
Other chronic conditions (%) 18 (62.0) 12 (52.2) 15 (48.4) Abbreviations: PPSV23, 23-valent pneumococcal polysaccharide vaccine; PCV-13, 13-valent pneumococcal conjugate vaccine. 3.2. Kinetics of GMFR of IgG The kinetics of GMFR of IgG in the 0.5-y interval, 1.0-y interval, and single...
Benefits of pneumococcal conjugate vaccine programs have been linked to the vaccine’s ability to disrupt nasopharyngeal carriage and transmission. The 10-valent pneumococcal vaccine (PCV10) was included in the Expanded Program on Immunization (EPI) in Sindh, Pakistan in February 2013. This study was...
A significant action of the host immune response, both natural and vaccine-induced7,15, has been demonstrated to affect PCV2 evolution, likely contributing to enhance the high genetic variability of this worldwide distributed virus. A noteworthy intra-host variability has been demonstrated in PCV2 ...
Abstract We conducted nucleotide and amino acid sequence alignment and phylogenetic analysis of porcine circovirus ORF2 (Cap protein) from 17 PCV2-positive clinical samples from nine different northern Vietnamese provinces (Mar 2018–Nov 2020), four local vaccines, and 77 reference strains. We ident...
This study aimed to evaluate the efficacy of a new trivalent vaccine containing inactivated Porcine Circovirus 1-2a and 1-2b chimeras and a Mycoplasma hyopneumoniae bacterin administered to pigs around 3 weeks of age. This trivalent vaccine has already been proved as efficacious in a split-dose ...
A single vaccination was performed at three weeks of age approximately with 2 mL of a trivalent vaccine containing inactivated cPCV-1/2a, cPCV-1/2b chimeras and M. hyopneumoniae bacterin (CircoMax Myco®, Zoetis Inc., Lincoln, NE, USA) by IM route in the neck. Non-vaccinated pigs ...
field have circulating maternal antibodies at three weeks of age, when the primary vaccine is administered. Hence, the objective of this study was to test the efficacy of the two-dose regimen of the Fostera PCV vaccine containing the oil adjuvant against PCV2d challenge in a weanling pig ...
Improving the availability and characterization of cases has direct relevance to WHO's global roadmap for defeating meningitis by 2030, which set targets for vaccine-preventable meningitis surveillance, including for pneumococcal meningitis. In particular, the roadmap calls for strengthening of surveillance...