STEROIDSPneumocystis jirovecii pneumonia (PCP) is increasingly reported in patients without HIV. Corticosteroids are a major risk factor, with up to 90% of patients receiving corticosteroid treatment prior to th
prophylaxis therapy once CD4 count > 200 cells/μL. Patients on chronic steroids : Continue TMP-SMX until steroids are < 20 mg daily.Patients receiving chemotherapy or immunosuppressive agents temporarily: TMP-SMX until treatment is complete and the immune system has recovered.Transplant...
In this trainee-led QI initiative, we investigated rates of appropriate PCP prophylaxis at a tertiary care cancer center and surveyed clinicians regarding barriers to prescribing prophylaxis.Methods:An interprofessional, multidisciplinary team consisting of hematology-oncology fellows and cancer-center level ...
PCP Prophylaxis in Patients With IBD on Chronic Steroids: A Need for Clearer Guidelinesdoi:10.1016/j.chest.2016.08.173Kathuria, SiddarthSequeira, HermanScatena, RobynElsevier Inc.Chest
In 88% of patients who received steroids, dosage was either lowered or given as pulse-therapy in the 2 weeks preceding the onset of symptoms. Only 1 patient was on PCP prophylaxis at diagnosis and only 8 (16%) patients had previously been given PCP prophylaxis. At diagnosis, 78% of ...