www.nature.com/scientificreports OPEN received: 12 June 2015 accepted: 29 September 2015 Published: 27 October 2015 Molecular architecture of the Ub-PCNA/Pol η complex bound to DNA Wilson C. Y. Lau1,2, Yinyin Li3, Qinfen Zhang3 & Michael S. Y. Huen1,2 Translesion...
ATAD5 also enhances the Ub–PCNA deubiquitination by USP7 and USP11 through specific interactions. ATAD5 promotes the distinct deubiquitination process of UAF1–USP1, USP7, and USP11 for poly-Ub–PCNA. Additionally, ATAD5 mutants deficient in UAF1-binding had increased sensitivity to DNA-...
It was found that expression of both N- and C-terminal PCNA•Ub fusions conferred significant tolerance to ultraviolet (UV)-induced DNA damage. Surprisingly, depletion of Polη, a TLS polymerase dedicated to bypassing UV-induced pyrimidine dimers, did not alter tolerance conferred by PCNA•Ub...
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A.L. Kirchmaier, Ub-family modifications at the replication fork: regulating PCNA-interacting components, FEBS Lett. 585 (2011) 2920-2928.Kirchmaier AL (2011) Ub-family modifications at the replication fork: regulating PCNA-interacting components. FEBS Lett 585(18):2920–2928. : 10.1016/...
2011. Ub-family modifications at the replication fork: regulating PCNA-interacting components. FEBS Lett 585:2920- 2928.A.L. Kirchmaier, Ub-family modifications at the replication fork: regulating PCNA-interacting components, FEBS Lett. 585 (2011) 2920-2928....