2. Hendriks LEL, Subramaniam DS, Dingemans AC. Central Nervous System Metastases in Lung Cancer Patients: From Prevention to Diagnosis and Treatment. Editorial. Front Oncol. 2018;8:511. 3. Arrieta O, Saavedra-Perez D, Kuri R, et ...
18.Goldman JW, Dvorkin M, Chen Y, et al. Durvalumab, with or without tremelimumab, plus platinum-etoposide versus platinum-etoposide alone in first-line treatment of extensive-stage small-cell lung cancer (CASPIAN): updated ...
ADVANCED BREAST CANCERPrevious clinical studies have suggested that 4'-O-tetrahydropyranyl-doxorubicin (THP) as well as 5-fluorouracil/high-dose folinic acid (5-FU/HDFA) are active and well-tolerated drugs in breast cancer treatment. This phase I-II study was designed to determine the maximum...
1 Aune D, Sen A, ó'Hartaigh B, etal. Resting heart rate and the risk of cardiovascular disease, total cancer, and all-cause mortality - a systematic review and dose-response meta-analysis of prospective studies. Nutr Metab Cardiovasc Dis 2017;27:504–17. 2 Gaba P, Gersh BJ, Muller J...
2. Hendriks LEL, Subramaniam DS, Dingemans AC. Central Nervous System Metastases in Lung Cancer Patients: From Prevention to Diagnosis and Treatment. Editorial. Front Oncol. 2018;8:511. 3. Arrieta O, Saavedra-Perez D, Kuri R, et al. Brain metastasis development and poor survival associated ...
目的探讨心理弹性和运动恐惧在冠心病患者经皮冠状动脉介入治疗(PCI)后家庭功能与运动依从性间的链式中介作用。 方法采用便利抽样法,选取2022年12月—2023年4月湖州市第一人民医院收治的行PCI的冠心病患者为调查对象,采用一般资料调查表、Connor-Davidson韧性量表(CD-RISC)、心脏病患者运动恐惧量表(TSK-SV Heart)、家庭...
Bruker offers advanced preclinical imaging solutions for a broad spectrum of application fields, such as oncology, neurology, cardiology, inflammation, infectious diseases, cancer research, functional and anatomical neuroimaging, orthopedics, cardiac imaging and stroke models. ...
T cell-based immunotherapies have revolutionized cancer treatment, yet durable responses remain elusive. Here we show that PCIF1, an RNA N6 2′-O-dimethyladenosine (m6Am) methyltransferase, negatively regulates CD8+ T cell antitumor responses. Whole-body or T cell-specific Pcif1 knockout (KO) ...
in gene therapy, vaccination and cancer treatment. Our studies also indicate that PCI of bleomycin is superior to PDT in targeting the tumor periphery and that this is partly the cause of the improved treatment effect of PCI as compared to PDT. Recent advances in understanding the mechanisms of...
Histone deacetylase 8 (HDAC8) is a well-known epigenetic regulator for cancer therapy. However, developing targeted inhibitors for HDAC8 is challenging due to a limited understanding of its structural dynamics, which is crucial for ligand interaction. Here, we employed an integrated approach, includi...