EGFR and HER2 can form homodimers or heterodimers after activation to activate intracellular signaling pathways, such as RAS/RAF/MEK/ERK, PI3K/AKT/mTOR, Src kinase, and STAT transcription factors associated with tumorigenesis, cancer progression, and drug resistance27,28. In this study, we employed...
Download:Download full-size image Fig. 6. Relative total RuBisCO activity (A) and relative specific RuBisCO activity (B) of engineeredSynechocystisPCC 6803 strains control (WT+Kmr-vector), FL50, FL52, control (WT+Kmr-genome), FL75, and FL76. Total RuBisCO activity was calculated as14C inco...
Full size table Recombinant OaCLH shares a higher degree of amino acid sequence identity with other cyanobacterial chlorophyllases (51–71%) than with plant chlorophyllases (25–32%). Clustal Omega was used to align the amino acid sequence of OaCLH with eight previously reported cyanobacterial chl...
PCC was established in 1993, and it’s a state owned company by Tianjin University which is ranking No.1 in chemical engineering in China. PCC has a factory size of 145,064m2and currently employs more than 350 people with various responsibilities in design and R&D, project management, enginee...
Full size image An intramolecular disulfide bridge in the BSE domain influences theSynDLP GTPase activity TheSynDLP structure indicated the formation of an intramolecular disulfide bridge between C8 and C777 that covalently connects the BSE1 and BSE3 domains (Fig.3a). In fact, the migration behavi...
J Biol Chem. 1993;268(13):9329–36. 9. Beard SJ, Hayes PK, Pfeifer F, Walsby AE. The sequence of the major gas vesicle protein, GvpA, influences the width and strength of halobacterial gas vesicles. FEMS Microbiol Lett. 2002;213(2):149–57. 10. Walsby AE, Hayes PK. Gas vesicle...
5A). In the operon case, the enzymes were able to retain their full functions, while still being translated from the same mRNA, thereby optimizing spatial and temporal proximity to each other without potential compromise of function. The constructs were designated IspA:CnVS-fus and IspA:CnVS-op...
Full size image Growth performance under different conditions To test the tolerance of PCC 11901 to different salinities, growth was assessed in the presence of a wide range of NaCl concentrations, from 0 to 10% (w/v), where sea water is ≈3.5% NaCl (Fig. 1b, Supplementary Fig. 3a–...
An equal volume of glass beads pre-wetted with thylakoid buffer was added to the cell suspension, and the cells were broken in a Bead-Beater with an ice-jacketed sample chamber in six breakage cycles at full speed (30 s of burst, followed by 5 min of chilling). The homogenate was ...
J Biol Chem 264: 19200–19207 (1989). Google Scholar Belknap, WR, Haselkorn, R: Cloning and light regulation of expression of the phycocyanin operon of the cyanobacterium Anabaena. EMBO J 6: 871–884 (1987). Google Scholar Zurawski, G, Bottomley, W, Whitfeld, PR: Structures of the ...