Literature reviews of the gene product, as well as the first clinical results of the Progensa PCA3 test, are presented.doi:10.1586/14737159.7.5.491de la TailleAlexandreExpert Review of Molecular Diagnosticsde la Taille A (2007) Progensa PCA3 test for prostate cancer detection. Expert Rev Mol ...
系统标签: biopsy prostate assay men urine cancer AdultUrology PCA3MolecularUrineAssayforProstate CancerinMenUndergoingRepeatBiopsy LeonardS.Marks,YvesFradet,InaLimDeras,AmyBlase,JeannetteMathis, SheilaM.J.Aubin,AnthonyT.Cancio,MarieDesaulniers,WilliamJ.Ellis, HarryRittenhouse,andJackGroskopf OBJECTIVES Menwit...
thepca3testforguidingrepeatbiopsyofprostatecancer OpenAccess ORIGINALARTlCLE AsianJournalofAndrology(2014)16。487-492 ◎2014AJASIMM&SJTUAllrightsreserved1008—682X asiaandrocom;ajandrologycorn ThePCA3testforguidingrepeatbiopsyofprostate canceranditscut--offscore:asystematicreviewand meta··analysis YongLUG,...
PCA3 refers to a noncoding messenger RNA that is found to be significantly elevated in more than 90% of men with prostate cancer (PCa), but not in normal prostatic glands or benign prostatic hypertrophy. It is a urine-based diagnostic test approved by the FDA to determine the need for re...
PCA3 is a non-coding mRNA molecule that is overexpressed in prostate cancer. The purpose of this study is to evaluate the utility of the PCA3 molecular urine test scores to predict adverse pathologic features and catheterized specimen collection. Hundred men with clinically localized prostate cancer...
Prostate cancer is a tumour in which a biomarker,prostate-specific antigen(PSA), is employed to assist in diagnosis. However, an elevated PSA per se is not a specific enough test for prostate cancer but rather an indicator of its possibility, with histological confirmation usually via transrectal...
Several studies evaluated its value for prostate cancer diagnosis. These papers are consistent with significant statistical accuracy of measure of the urinary number of PCA3 copies (PCA3 test). While sensitivity is slightly weaker than that of seric PSA, specificity as well as positive and negative ...
(PCA3) testing to inform decisions for when to rebiopsy previously biopsy-negative patients for prostate cancer or to inform decisions to conduct initial biopsies for prostate cancer in at-risk men (e.g., previ- ous elevated prostate-specific antigen test or suspicious digital rectal examination)...
As a clinical test for early prostate cancer, heightened specificity is also seen in urine containing prostate cells from men with the disease. PCA3 gene testing holds valuable potential in PSA quandary situations: (1) men with elevated PSA levels but no cancer on initial biopsy; (2) men ...
Background Prostate cancer (PCa) is the most common male cancer in Europe and the US. The early diagnosis relies on prostate specific antigen (PSA) serum test, even if it showed clear limits. Among the new tests currently under study, one of the most promising is the prostate cancer gene...