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[Studies on the disc method for the determination of bacterial sensitivity to ribostamycin (author's transl)] The MIC''s of sulfobenzylpenicillin (SB-PC) were determined by the two-fold serial agar-dilution method for 108 bacterial strains of 21 species. The diameters of inhibition zones of ...
Fosmidomycin represents a specific high-affinity inhibitor of IspC. Very recently, its anti-malaria activity in man has been demonstrated in clinical trials. Here, we present the crystal structure of Escherichia coli IspC in complex with manganese and fosmidomycin at 2.5 Å resolution. The (...
Regulated Expression of an Environmental DNA-Derived Type II Polyketide Gene Cluster in Streptomyces Hosts Identified a New Tetracenomycin Derivative TCM Y Lishuang Nie Mingming Cao Zhiyang Feng Current Microbiology(2022) Advertisement Nature Communications (Nat Commun)ISSN2041-1723(online) ...
针对这一挑战，哈佛大学研究团队采用全人工合成的方式设计出一种新型抗生素（克雷霉素，Cresomycin），其通过提高与细菌核糖体的结合能力克服了传统抗生素的耐药性，体内/外试验显示可有效杀灭多种耐药细菌。目前，这项研究成果已经以“An antibiotic preorganized for ribosomal binding overcomes antimicrobial resistance”...
伊马替尼/格列卫 按照字母顺序常用化疗药物中英文对照 A Aclacinomycin ACLA 阿克拉霉素 Alemtuznmab 阿来组单抗, 抗CD52 嵌合抗体 All-trans retinoic acid, ATRA, RA 全反式维甲酸, 维A酸 Aminoglutethimide AG 氨基导眠能, 氨鲁米特, 氨苯哌酮 Anastrozole, Arimidex 瑞宁得, 阿纳托唑, 阿那曲唑 ...
A novel proteinous substance KUP-PC, which is produced by culturing proteinous substance KUD-PC producing organisms belonging to the genus Streptosporangium. KUD-PC increases the antitumor activity of the anti- tumor substance, sporamycin.doi:US4529542 AIwao UmezawaKanki KomiyamaUS...
Susceptibility of 539 Gram-positive and Gram-negative anaerobes to new agents, including RP59500, biapenem, trospectomycin and piperacillin/tazobactam Susceptibilities of 539 Gram-positive and Gram-negative anaerobes were tested by agar dilution against 15 new and existing antimicrobial agents. Organism...
支原体最突出的结构特征是没有细胞壁,一般来讲,对作用于细胞壁生物合成的抗生素,如万古霉素等完全不敏感;对多粘菌素(polymycin)、利福平、磺胺药物普遍耐药。对支原体最有抑制活性及常用于支原体感染治疗的抗生素是四环素类、大环内酯类及一些喹诺酮;其他类抗生素如基糖苷类、霉素对支原体有较小抑制作用,所以常不用来...
Aclacinomycin (ACLA) and doxorubicin (DOX) were used at subtoxic concentrations to induce erythroid differentiation in the human leukemic cell line K562. C... F Morceau,B Chenais,R Gillet,... - 《Cell Growth Differ》 被引量: 63发表: 1996年 ...