Considering that the prevalence of antibiotic-resistant pathogenic bacteria is largely increasing, a thorough understanding of penicillin-binding proteins (PBPs) is of great importance and crucial significance because this enzyme family is a main target of β-lactam-based antibiotics. In this work, ...
DM处理组水稻根际微生物多样性指数高于对照组。Candidatus Koribacter、Azospirillum和Kroibacteriaceae相对丰度分别从对照组的2.4%、2.3%和3.8%显著增加到10dDM处理后的3.7%、5.4%和7.5%。Bdellovibrio 和Methylibium属的相对丰度分别从对照组的5.5%和1.1%下降到10dDM暴露后的3.2%和0.3%(图3D)。Ellin6513和Koribacter...
PBP10 is a 10-AA peptide with rhodamine conjugated at its N terminus, exerts bactericidal activity against gram-positive and gram-negative bacteria and limits microbial-induced inflammatory effects[2]. [1]. Ewelina Piktel, et al. Inhibition of inflammatory response in human keratinocytes by ...
structure-based sequence comparison of class B PBPs from rod-like bacteria using the closed form ofH. pyloriPBP2 indicates that residues that line the head/anchor interface display clear similarities among class B enzymes (Fig.2c). In addition, in structures of unbound class B PBPs from both...
靶向铜绿假单胞菌粘肽合成酶PBP3的抗菌先导化合物的虚拟筛选与活性研究.pdf,Dissertation SubmittedtozhejiangGongshang Doctor’s of Un如e体j锣for Degllee Enginee血g VIRT【7AI,SCREEN时GAND ANⅡBACⅡ:RIALACⅡVITY OFLE√气D COMPOUNDS卫讯GEllNG1’OPENIC几LⅡ呵.
(spac) promoter; the resulting bacteria were unable to grow in the absence of inducer. In contrast, the deficit in PBP2 caused by inhibition of transcription of the pbp2 gene did not block growth of a methicillin-resistant S. aureus strain expressing the extra penicillin-binding protein PBP2A...
We show here that a PBP1 knockout strain is affected in the formation of the asymmetric sporulation septum and that green fluorescent protein-PBP1 localizes to the sporulation septum. Localization of PBP1 to the vegetative septum is dependent on various cell division proteins. This study proves ...
FibA and FibB belong to a family of proteins of Gram-positive bacteria involved in the formation of interpeptide bridges, thus representing interesting new targets for antimicrobial compounds for this group of pathogens. 2000 Federation of European Microbiological Societies. Published by Elsevier Science...
A structure-based sequence comparison of class B PBPs from rod-like bacteria using the closed form of H. pylori PBP2 indicates that residues that line the head/anchor interface display clear similarities among class B enzymes (Fig. 2c). In addition, in structures of unbound class B PBPs ...
专利标题: PBP2-a蛋白的单克隆抗体和同源序列用于由厚壁菌门的细菌引起的免疫诊断和感染的处理 专利标题(英):Monoclonal antibodies against the pbp2-a protein and homologous sequences for the treatment of infections by and immunodiagnostics of bacteria of the firmicutes phylum 申请号:CN201080043628.X 申...