By attaching antibodies to the bubbles and binding those antibodies with antigen receptors on target cell populations, the bubbles will gently carry target cells to the top of the sample container. This is typically done through negative selection, meaning the bubbles lift unwanted substances to the...
meaning that clones of T cells with different specificities express different TCRs. In the functional TCR, the α and β heterodimers are associated with a complex of four other invariant signaling chains, collectively called CD3, which are required for the cell-surface expression of the antigen ...
Although the advent of single-cell RNA sequencing has made it possible to measure gene expression of specific blood cell types, there remain financial and technical barriers to its widespread use. Hence, the most common methods of blood RNA profiling either investigate RNA extracted from all blood...
In some embodiments, the AACs are prepared by a process comprising: a) passing a cell suspension comprising a population of input PBMCs through a cell-deforming constriction, wherein a diameter of the constriction is a function of a diameter of the input PBMCs in the suspension, thereby ...
By attaching antibodies to the bubbles and binding those antibodies with antigen receptors on target cell populations, the bubbles will gently carry target cells to the top of the sample container. This is typically done through negative selection, meaning the bubbles lift unwanted substances to the...
T cell cultures are a valuable tool in food research to perform studies within the food allergy field. Their main applications aim to analyze immunological responses towards food protein antigens to gain further insights into the mechanisms responsible f
Chapter 16 PBMC-Derived T Cells Daniel Lozano-Ojalvo, Rosina López-Fandiño, and Iván López-Expósito Abstract T cell cultures are a valuable tool in food research to perform studies within the food allergy field. Their main applications aim to analyze immunological responses towards food ...