自身免疫性肝病(autoimmune liver disease,AILD)是一组由异常免疫介导的以肝脏炎症性损伤、肝功能异常为特征的自身免疫性疾病,包括原发性胆汁性胆管炎(PBC)、自身免疫性肝炎(AIH)、原发性硬化性胆管炎(PSC)等。其临床表现各异, 发病...
AIH-PSC是一种相对少见的综合征，主要见于儿童、青少年、中年［39-40］。AIH-PSC通常是序贯发生，典型表现为AIH先发病，数年后出现PSC［41］。研究［6］显示，AIH-PSC患者的炎症性肠病发生率较高，高于单纯AIH，与单纯PSC相当。2.2 临床特点 AIH-PSC无特异性临床表现，主要为瘙痒、黄疸、腹痛等；血清学通常有...
学术前沿|Hepatology:IL-31与NASH、PSC、PBC患者皮肤瘙痒的相关性 2023年1月,吉利德科学研究人员在期刊Hepatology(IF=17.2976)以“IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases and is farnesoid X receptor responsive in NASH”为题发表IL-31对肝病患者瘙痒的研究...
Fibrosis and Prognosis Assessment Using Liver Stiffness in Patients with PBC and PSCPrimary biliary cholangitis and primary sclerosing cholangitis (PSC) are the two most frequent chronic cholestatic liver diseases in adults. These cholangiopathies are characterized by progressive......
Ocaliva(obeticholic acid,OCA)是Intercept开发的一款创新药物法尼酯X受体(FXR)激动剂,这是一种人类胆汁酸模拟物,目前正开发用于多种慢性肝脏疾病的治疗,包括原发性胆汁性胆管炎(PBC)、非酒精性脂肪性肝炎(NASH)、原发性硬化性胆管炎(PSC)、胆道闭锁。此前,FDA已授予OCA治疗伴有肝纤维化的NASH的突破性药物资格、治...
[2]Foundation for Hepatitis Prevention and Control; Chinese society of Infectious Disease and Chinese Society of Hepatology, Chinese Medical Association; Liver Disease Committee of Chinese Research Hospital Association. Consensus on...
当当书之源外文图书在线销售正版《预订 AUTOIMMUNE LIVER DISEASES: AUTOIMMUNE HEPATITIS, PBC, AND PSC, An Iss [ISBN:9780443121456]》。最新《预订 AUTOIMMUNE LIVER DISEASES: AUTOIMMUNE HEPATITIS, PBC, AND PSC, An Iss [ISBN:9780443121456]》简介、书评、试读、价
PBC-PSC
PBC: Diagnosis PBC: Differential diagnosis PBC female +++ pruritus+++ ALT/ASL AKP/rGT AMA-M2 ERCP- Sjogren AIH young and middle age femle pruritus+ ALT/AST AKP/rGT ANA/SMA/LKM1/SLA ERCP - SLE/RA PSC male++ pruritus++ ALT/ASL AKP/rGT ANCA ERCP+ UC 治 疗 PBC: therapeutic agents ...
第一页，编辑于星期日：十五点四分。WhatisPrimaryBiliaryCirrhosis （PBC）？•Etiologyunknown•Chronicnonsuppurativedestructive cholangitisexclusivelyintrahepaticbileducts 第二页，编辑于星期日：十五点四分。病原学 PBC发病原因不清楚，有以下因素：1、遗传因素2、环境因素3、免疫学的因素4、细菌学的因素5、淋巴...