1.《Zakim and Boyer’s Hepatology: A Textbook of Liver Disease》(第 7 版) 2.《Yamada’s Textbook of Gastroenterology》(第 6 版) 3.《Autoantibodies》(第 3 版) 4. Uptodate 临床顾问
展开临床表现PBC特有表现 ① 乏力(fatigue) ② 瘙痒(pruritis) ③ 门脉高压(portal hypertension) ④ 代谢性骨病(metabolic bone disease) ⑤ 黄色瘤(xanthomata) ⑥ 脂溶性维生素吸收不良(fat soluble vitamin malabsorption) ⑦ 尿路感染(urinary tract infection) ⑧ 恶性肿瘤(malignancy)伴随疾病 ① 甲状腺功能障碍...
［21］CARBONE M, SHARP SJ, FLACK S, et al. The UKPBC risk scores: Derivation and validat ion of a scoring system for long-term prediction of end-stage liver disease in primary biliary cirrhosis［J］. Hepatology, 2016, 63(3): 930-950.［22］EFE C, TA瘙塁ILAR K, HENRIKSSON I...
[11] Hu C, Deng C, Song G, et al. Prevalence of autoimmune liver disease related autoantibodies in Chinese patients with primary biliary cirrhosis. Dig Dis Sci, 2011,56:3357-3363. [12] John B V, Dahman B, Deng ...
12. Parés, A., et al., Long-term effects of ursodeoxycholic acid in primary biliary cirrhosis: results of a double-blind controlled multicentric trial. UDCA-Cooperative Group from the Spanish Association for the Study o...
Recurrence of Primary Sclerosing Cholangitis After Liver TransplantationJ. Transplant Proc. 2006 38(1):240-243.原发性硬化性胆管炎(PSC) 推荐意见- -诊断()对于具 33、有胆汁淤积生物化学表现的患者,若胆道成像具备PSC典型表现,且除外其 他原因所致者可诊断PSC(A1)。()对于疑诊PSC患者,应进行胆道成像检查,...
接受UDCA治疗≥12个月(稳定剂量用药≥3个月)或不耐受UDCA且未接受UDCA治疗≥3个月的PBC患者,入组时ALP≥1.67倍正常上限(upper limit of normal,ULN)和/或总胆红素>ULN且<2倍ULN,排除合并其他肝病、存在具有显著临床意义的肝功能失代偿、严重瘙痒和终末期肝病模型(model for end⁃stage liver disease,MELD)评分...
[12] Harrison SA, Taub R, Neff GW, et al. Resmetirom for nonalcoholic fatty liver disease: a randomized, double-blind, placebo-controlled phase 3 trial. NAT MED. 2023;29(11):2919-28. [13] Jones D, Boudes P, Swain MG, et al. Seladelpar (MBX-8025), a selective PPAR-δ agonis...
[12] Harrison SA, Taub R, Neff GW, et al. Resmetirom for nonalcoholic fatty liver disease: a randomized, double-blind, placebo-controlled phase 3 trial. NAT MED. 2023;29(11):2919-28. [13] Jones D, Boudes P, Swain MG, et al. Seladelpar (MBX-8025), a selective PPAR-δ agonis...
第1页/共47页PBC和PSC诊断和治疗共识讲解第2页/共47页原发性胆汁性肝硬化(又名原发性胆汁性胆管炎)诊治共识 (2015)安徽省感染病学会暨肝病学分会第3页/共47页原发性胆汁性肝硬化(PBC)PBC定义PBC诊治推荐意见原发性胆汁性肝硬化(primary biliary cirrhosis, PBC) 是一种慢性肝内胆汁淤积性疾病。其发病机制...