When local auxin levels increase, indole 3-acetic acid serves as the “molecular glue” to form a co-receptor with one of the six auxin perceiving F-box proteins and an Aux/IAA (10). This interaction results in polyubiquitination and degradation of the Aux/IAA repressor proteins (11), ...
Detection of recombinant PB1-F22.9. Detection of PB1-F2 in IAV-infected cells.2.10. SPR measurements2.11. AFM measurements3. Results and discussions3.1. Electrochemical polymerization of copoly(Py-PyFcNHP)3.2. Construction and characterization of the biosensor.3.3. Electrochemical detection of ...
I中文摘要A型流感病毒PB1-F2与p58IPK相互作用及对PKR信号通路的调控流行性感冒病毒(influenzavirus)简称流感病毒,属于正黏病毒科单股负链RNA病毒,能够造成人、狗、马、猪及禽类等患流行性感冒。在A、B、C三型流感病毒中,A型流感病毒(influenzaAvirus,IAV)的致病性最强,经常造成暴发、流行或大流行,是引起畜禽死亡以...
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甲型流感病毒PB1-PA蛋白作用位点的发现与分析
cell lysates were Western blotted to detect the expression level of PB1. We found that the expression of PB1 protein was dramatically impaired when SQSTM1/p62 was co-expressed. However, the suppressing effect of SQSTM1/p62 on PB1 expression was antagonized along with the gradient increase in...
We found that PR8 PB1-F2 co-localizes and interacts with duck MAVS in DF-1 cells and inhibits type I interferon induction. Finally, we show that PB1-F2 abrogates TRIM25 mediated ubiquitination of RIG-I, while an NS1 variant from this strain does not. 2. Materials and Methods 2.1. ...
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