1A, H7N9 PB1-F2 peptide induced IL-1β secretion by macrophages in a dose-dependent manner, similar to that observed with PR8 PB1-F2. Furthermore, H7N9 PB1-F2 peptide corresponding to the sequence changes associated with crossover from avian to human (G70E and S77L) also induced IL-...
When local auxin levels increase, indole 3-acetic acid serves as the “molecular glue” to form a co-receptor with one of the six auxin perceiving F-box proteins and an Aux/IAA (10). This interaction results in polyubiquitination and degradation of the Aux/IAA repressor proteins (11), ...
cell lysates were Western blotted to detect the expression level of PB1. We found that the expression of PB1 protein was dramatically impaired when SQSTM1/p62 was co-expressed. However, the suppressing effect of SQSTM1/p62 on PB1 expression was antagonized along with the gradient increase in...
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All peptides were purchased from Shanghai ChinaPeptides Co., Ltd. A549 cells in 24-well plates were transfected with 1 μg of a Gaussia luciferase reporter plasmid pPolI-Gluc to detect virus infection as described previously49. 10 h post transfection, peptides were added into the medium...
0.1µF A IIN1 VIN1 NC NJM2898 VIN2 0.1µF A IIN2 VIN2 NOISE BYPASS2 CONTROL2 Cp=0.01µF VOUT2 VOUT2 GND A I CONT2 V VCONT2 V VOUT2 IOUT2 1.0µF*3 (ceramic) *3 Vo≤2.6V version: Co=2.2µF(ceramic) Ver.2004-12-22 -3- NJM2898 TYPICAL APPLICATION 1 In ...
I中文摘要A型流感病毒PB1-F2与p58IPK相互作用及对PKR信号通路的调控流行性感冒病毒(influenzavirus)简称流感病毒,属于正黏病毒科单股负链RNA病毒,能够造成人、狗、马、猪及禽类等患流行性感冒。在A、B、C三型流感病毒中,A型流感病毒(influenzaAvirus,IAV)的致病性最强,经常造成暴发、流行或大流行,是引起畜禽死亡以...
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