Uses Pazopanib Hydrochloride (GW786034) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM, respectively - See more at: http://www.selleckchem.com/products/Pazopanib-Hyd...
Available as pazopanib hydrochloride; dosage expressed in terms of pazopanib.AdultsRenal Cell CarcinomaOral800 mg once daily. Continue therapy for as long as the patient derives clinical benefit from the drug or until unacceptable toxicity occurs....
Uses Pazopanib Hydrochloride (GW786034, Votrient, Armala) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM, respectively. ...
The invention discloses dosage regimens, therapeutic methods, controlled release preparations and combined treatments of HDAC inhibitors, pharmaceutically acceptable saltssalts thereof, and pazopanib (or salts of the pazopanib, such as pazopanib hydrochloride).Balasubramanian Sriram...
Pazopanib Hydrochloride (GW786034, Votrient, Armala) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM, respectively. Uses Pazopanib is a potent and selective multi-targete...
Pazopanib Impurity 3 2-methyl-5-((4-(methyl(3-methyl-2H-indazol-6-yl)amino)pyrimidin-2-yl)amino)benzenesulfonamide Pazopanib Impurity 52(Hydrochloride) VEGFR-2-IN-6, 10 mM in DMSO CAS: 444731-47-9 MF: C20H21N7O2S MW: 423.49 Mol File: 444731-47-9.molMore...
Pazopanib 13CD3cas:1261734-88-6 Pazopanib 13C D3 Hydrochloridecas:1261398-44-0 Ziprasidone Ring-opened IMpurity (IMpurity C)cas:1798033-44-9 Ketoconazole Impurity 9 (Ketoconazole Hydroxymethyl Impurity)cas:170210-42-11. Names and Identifiers 2. Other Information 3. Realated Product Infomation Produ...
Pazopanib hydrochloride is a white to slightly yellow solid. It is very slightly soluble at pH 1 and practically insoluble above pH 4 in aqueous media. Tablets of VOTRIENT are for oral administration. Each 200-mg tablet of VOTRIENT contains 216.7 mg of pazopanib hydrochloride, equivalent to 200...
MSDS Information Pazopanib Impurity 47 Usage And Synthesis Uses2-[(2,3-Dimethyl-2H-indazol-6-yl)amino]-4(3H)-pyrimidinone is an intermediate in the synthesis of 5-((2-((2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-4-yl)amino)-2-methylbenzenesulfonamide Hydrochloride (D474433) wh...
(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide hydrochloride has a particle size distribution such that more than 90% of the particles are between 0.61 and 10.0 microns;(ii) guar gum, wherein said guar gum is present from 3.0% to 8.0% by weight...