Pazopanib Hydrochloride structure CAS No. 635702-64-6 Chemical Name: Pazopanib Hydrochloride Synonyms Pazopanib hydrochloride;Pazopanib HCl;CS-462;ArMala;786034;GW-786034B;GW786034 HCl;Votrient HCl;Pazopanib HCI;Unii-33Y9anm545 CBNumber: CB42495435 Molecular Formula: C21H24ClN7O2S Molecular ...
GW786034 (Hydrochloride); GW786034; Pazopanib Hydrochloride; GW786034 HCl; Votrient HCl; Pazopanib Hydrochloride; Votrient HCl; GW786034 HCl; GW786034 Armala 中文名称(Chinese Name) 盐酸帕唑帕尼 靶点(Target) VEGFR1; VEGFR2; VEGFR3; FGFR; PDGFR; VEGFR/PDGFR/FGFR/c-Kit/ c-Fms ...
pazopanib hydrochloride molecular structure 3d flat model hydrochloride salt structural chemical formula view from a microscope,站酷海洛,一站式正版视觉内容平台,站酷旗下品牌.授权内容包含正版商业图片、艺术插画、矢量、视频、音乐素材、字体等,已先后为阿里
Pazopanib hydrochloride has the following chemical structure: Pazopanib hydrochloride is a white to off-white powder. It is very slightly soluble at pH 1 and practically insoluble above pH 4 in aqueous media. Pazopanib tablets are for oral use. Each 200 mg tablet of pazopanib contains 200 mg ...
Pazopanib hydrochlorideis an oral multi-targetedtyrosine kinase receptor inhibitorwith anti-tumor activity.Pazopanibinhibitsvascular endothelial growth factor receptor(VEGFR)-1, -2, and-3, platelet-derived growth factor receptor (PDGFR), and ckit, which may result in inhibition of angiogenesis in tumors...
Chemical name:Pazopanib Hydrochloride ; CAS NO:635702-64-6; Molecular Formula:; Molecular Weight:473.9866 ; EINECS:
Used as its hydrochloride salt for treatment of kidney cancer. PazopanibSupplier 3.2 Description Pazopanib, with the chemical formula C21H23N7O2S, has the CAS number 444731-52-6. It is a tyrosine kinase inhibitor used in the treatment of advanced renal cell carcinoma and soft tissue sarcoma. ...
Pazopanib Hydrochloride (GW786034, Votrient, Armala) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM, respectively. ...
Cells were then treated with serially diluted concentrations of acetami- nophen (APAP, Sigma) and pazopanib hydrochloride (Selleck Chemicals) in the basal differentiation medium supplemented with 20 ng/ml HGF (R&D systems), 100 ng/ml Follistatin-288 (R&D systems) and 20 ng/ml Oncostatin...
Commercially, it is formulated as a hydrochloride salt, which is slightly soluble at very low pH (1) but practically insoluble at pH values C4 in aqueous matrices [8]. The permeability of pazopanib was measured in vitro by Caco-2 monolayer experiments, with the results point- ing towards ...