You should not use Paxlovid if you are allergic to the active ingredients nirmatrelvir and ritonavir or any of the inactive ingredients. A list of ingredients is at the bottom of this page. Some drugs have drug interactions with Paxlovid, and they should not be used with Paxlovid, such ...
Table 1 provides a listing of clinically significant drug interactions, including contraindicated drugs [see Contraindications (4) and Warnings and Precautions (5.1)]. Drugs listed in Table 1 are a guide and not considered a comprehensive list of all possible drugs that may interact with PAXLOVID....
Take Drug Interactions Seriously: Paxlovid in Transplant Patients Taking Tacrolimusdoi:10.1681/ASN.20233411S1801bBatoul DekmakNika Samadzadeh TabriziEmmanuel A. Aydin-GhormozGeovani FaddoulKrishnakumar D. HongalgiAmerican Society of NephrologyJournal of the American Society of Nephrology...
The FDA European Union Authorization document has a more comprehensive list of possible drug interactions [72]. Considering the novelty of nirmatrelvir/ritonavir, not much is known about its long-term efficacy or any possible adverse effects. However, some studies have reported that nirmatrelvir/...
Since Paxlovid is cleared by the kidneys, dose adjustments may be required for patients with mild-to-moderate kidney disease. For patients with severe kidney disease—or who are on dialysis—or those with severe liver disease, P...
WARNING: SIGNIFICANT DRUG INTERACTIONS WITH PAXLOVID PAXLOVID includes ritonavir, a strong CYP3A inhibitor, which may lead to greater exposure of certain concomitant medications, resulting in potentially severe, life-threatening, or fatal events
the CDC reported on a real-world study that showed adults who took Paxlovid within five days of a COVID-19 diagnosis had a 51% lower hospitalization rate within the next 30 days than those who were not given the drug. The study included people who had been vaccinated or had a previous...
Severe, life-threatening, and/or fatal adverse reactions due to drug interactions have been reported in patients treated with PAXLOVID. The most commonly reported concomitant medications resulting in serious adverse reactions were calcineurin inhibitors (eg, tacrolimus, cyclosporine), followed by ...
Other errors included ordering the standard dose for patients with moderate renal impairment, not checking concomitant drug use or renal function to avoid drug-drug interactions, prescribing the incorrect quantity (eg, 30 tablets for moderate renal impairment dosing), and providing directions to take ...
the CDC reported on a real-world study that showed adults who took Paxlovid within five days of a COVID-19 diagnosis had a 51% lower hospitalization rate within the next 30 days than those who were not given the drug. The study included people who had been vaccinated or had a previous...