paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep ...
PAX7 基因简介 中英文全称:成对框基因7 paired box gene 7 分布:核 活性:转录 因子|顺序特异DNA 结合 参与:调控转录, DNA 依赖|抗 细胞凋亡|形态发生 病变:横纹肌肉瘤, 肺泡 OMIM/位置:167410 1p36.2-p36.12
配对框7基因的特异功能尚不清楚,但推测可能与肿瘤抑制有关,因为该基因与叉头结构域家族成员的融合与肺泡状横纹肌肉瘤有关已经发现了三个编码不同亚型的转录变体。 This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box ...
该文章通过对5个肌病家系的基因检测及相关功能验证,确认PAX7基因的双等位变异是导致这一类肌病的新的遗传原因。 入组患者 五个肌病患者,分别来自四个血缘关系不相关的家庭。1号——14岁男孩,来自加拿大;2号——5岁女孩,来自德国;3号——男孩(7岁时死亡),来自巴勒斯坦;4号——4岁男孩,来自沙特阿拉伯;5号——6...
The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Three transcript variants encoding different isoforms have been found for this gene....
2019年5月16日的GENETICS in MEDICINE杂志上发表了一篇名为《Biallelic variants in the transcription factorPAX7are a new genetic cause of myopathy》的文章。该文章通过对5个肌病家系的基因检测及相关功能验证,确认PAX7基因的双等位变异是导致这一类肌病的新的遗传原因。
Horst, The genomic organization and the full coding region of the human PAX7 gene, Genomics 45 (1997) 168 -174.Vorobyov, E., et al. 1997. The genomic organization and the full coding region of the human Pax-7 gene. Genomics 45: 168-174....
Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008] 基因名: PAX7 别名: HUP1,RMS2,PAX7B,MYOSCO 基因ID: 5081 Chromosome:(GRCh37) 1 Start: 18957500 End: 19075360 Strand: 信号通路: PAX7 基因突变与药物...
This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and
关键字:PAX7;Paired box gene 7;FLJ37460;HUP1;OTTHUMP00000002534;Paired box 7;Paired box homeotic ;PAX7_HUMAN; 公司简介 上海沪震实业有限公司是一家集研发、生产和销售于一体的生命科学实验室产品生物科技企业。主营产品:试剂盒,ELISA试剂盒,抗体,重组蛋白,血清,胎牛血清,细胞,原代细胞 细胞培养试剂,常用生...