paucimannose 少甘露糖 pauci- 少 mannose 甘露糖 甘露糖 mannose 一种单糖。分子式C5H11O5CHO。为多种多糖的组成成分。以游离状态存在于某些植物果皮中，如柑橘皮中，桃、苹果等水果中有少量游离的甘露糖，象牙棕榈子、酵母、红藻、血清球蛋白、卵类粘蛋白和结核杆菌中含有D-甘露糖的聚糖。如果是下...
ii) HNE- (top gel) and paucimannose-specific (bottom gel) immunoblotting of stimulated (+) and resting (-) human neutrophils showed spatiotemporal regulation of paucimannosylated HNE on the cell surface of activated neutrophils. Cell surface proteins were extracted by NHS-biotinylation and captured...
本发明公开了一种paucimannose特异性抗体制备的方法,本发明涉及paucimannose生物标记物(M2F和M3F)两种生物标记物引发小鼠免疫刺激所产生抗体的方法.所述抗体在对paucimannose相关疾病临床检测中的用途,与传统基因组学测序,糖组学分析以及高通量筛选等临床检测方法相比,通过抗体与血清中生物标记物的特异性结合可以更快,更...
The trimannosyl structure, also called paucimannose, is characteristic for all eukaryotic N-glycans. The unmodified structure is expressed abundantly in plants and invertebrates, whereas in normal mammalian tissue it has been detected in only very small amounts. We have developed a monoclonal antibody...
Plant synthesizing hypoallergenic paucimannose type N-glycan and uses thereofThe present invention relates to a plant for producing a protein containing a humanized low-mannose N-glycan, and a method for producing a protein containing a customized humanized low-mannose N-glycan using the aforementioned...
A method for producing a transgenic plant for a production of a protein containing hypoallergenic pauci-mannose-type N-glycan that does not include α1,3-fucose and β1,2-xylose residues but includes α1,6-fucose residue includes preparing the quadruple mutant (qm) plant, and transforming the...
Tai, B. Schmitz, Mannitou monoclonal antibody uniquely recognizes paucimannose, a marker for human cancer, stemness, and inflammation, J. Carbohydr. Chem. 31 (2012) 504-518.Zipser, B., Bello-DeOcampo, D., Diestel, S., Tai, M. H., and Schmitz, B. (2012) Mannitou Monoclonal ...
The present invention relates to a plant for producing a protein containing a humanized paucimannose N-glycan, and to a method for producing a protein containing a humanized customized paucimannose N-glycan, using the same.LEE, KYUN OHYOO, JAE YONG...
The present invention relates to a plant synthesizing a protein containing humanized paucimannose type N-glycan, and a method of producing the protein containing humanized customized paucimannose type N-glycan using the same. The plant according to the present invention can produce a protein ...
Plant synthesizing hypoallergenic paucimannose type N-glycan and uses thereofThe present invention relates to a plant for producing a protein containing a humanized low-mannose N-glycan, and a method for producing a protein containing a customized humanized low-mannose N-glycan using the aforementioned...