The patient was positive for alpha thalassemia trait; negative for mutation in Janus kinase 2, calreticulin, or myeloproliferative leukemia virus oncogene; and negative for reactive causes of thrombocytosis. Noticeably, a variant in atypical chemokine receptor 1 (ACKR1) (c.-67T>C, rs2814778) was...
Objectives: To determine the molecular basis in a Greek child suspected of having HbH disease and β-thalassemia trait.Methods: Standard hematology, Hb electrophoresis, and HPLC. Multiplex ligation-dependent probe amplification (MLPA), direct sequencing, and breakpoint characterization by NimbleGen fine...
The occurrence of Systemic lupus erythematosus (SLE) with Autoimmune hemolytic anemia (AIHA) has been only rarely reported in patients with Beta thalassemia trait.We here report a case of SLE presented with history of fever, giddiness associated with headache for three months and on physical examin...
Beta-ThalassemiaBeta-thalassemia, a blood disorder characterized by reduced or absent hemoglobin production, causing anemia and complications, seeks to introduce functional beta-globin genes into bone marrow cells via gene therapy. This enables the production of healthy red blood cells. Sickle Cell Disea...
The clinical picture in the α-thalassemia syndromes is related to the numbers of functional α-globin genes present.66 Deletion of 1 α-globin gene leads to an asymptomatic carrier state. Deletion of 2 α-globin genes leads to α-thalassemia trait with mild hypochromic, microcytic anemia. Delet...
Pseudo-Thrombocytosis Caused by Extreme Microcytosis in a Patient with Alpha Thalassemia TraitThrombocytosisMicrocytosisAlpha thalassemiaPeripheral smearIndian Journal of Hematology and Blood Transfusion -doi:10.1007/s12288-020-01297-6Alexander A. Slota...
Hyperparathyroidism and thalassemia trait in a patient with impacted teeth: A case report revealing the importance of detailed history taking and investigationsdoi:10.4103/0972-1363.167129VinodVijay ChandarShailaja SankireddySridevi KoduriAkshika Sharma...
A Case of Concurrent Sickle Cell Trait, Alpha Thalassemia, and G6PD Deficiency in a Pediatric Patientdoi:10.35248/2684-1266.21.7.129Vinay KrupadevJoshua KirbensAmina RafiqueLongdom Publishing S.L
Objectives: To determine the molecular basis in a Greek child suspected of having HbH disease and β-thalassemia trait.Methods: Standard hematology, Hb electrophoresis, and HPLC. Multiplex ligation-dependent probe amplification (MLPA), direct sequencing, and breakpoint characterization by NimbleGen fine...
BETA-ThalassemiaMYCOPLASMA pneumoniae infectionsAUTOIMMUNE hemolytic anemiaANEMIAKLEBSIELLA infectionsEditor An 83-year-old man with a history of beta-thalassemia trait (baseline haemoglobin 10 g/dl), coronary artery disease on aspirin, and prior gastrointestinal (GI) bleeds presented to the emergency ...