asimplerapproachtomeasuringpatients’perceptionsofseverityandsymptomchangemaybeparticularlyuseful forclinicalpractice.Theaimofthisstudywastoprovideevidenceofthevalidityofthe1-itemPatientGlobal ImpressionofSeverity(PGI-S)andImprovement(PGI-I)questionnairesforuseasoutcomemeasuresinthe treatmentofBPH-LUTS. Methods:Thiswas...
We evaluated a single-item Patient Global Impression-Severity (PGI-S) scale for assessing insomnia severity during the clinical development programme for suvorexant. The analyses used data from two randomised, double-blind, placebo-controlled, 3-month, Phase III clinical trials of suvorexant in ...
Global, single-question PROMs, such as the Patient Global Impression of Improvement (PGI-I) after treatment, are practical and have been shown to encompass consideration of all symptoms [12]. Owing to their brevity they are ideal in the modern NHS. Such brevity may increase clinician’s ...
by evaluating the content validity and relevance of 5 patient reported outcome (PRO) measures (PROMIS-Fatigue-8a, the PROMIS-Sleep Impairment-8a, the Epworth Sleepiness Scale (ESS), Patient-Global Impression of Severity (PGI-S)-Fatigue, and Patient-Global Impression of Change (PGI-C)-Fatigue)...
Patient global impression scale of improvement (PGI-I)Clinician global impression scale of improvement (CGI-I)Convergent validityAgreementDepressionBipolar disorderPsychologyrandomized control trialBackgroundConcordant with an increased emphasis on consumer engagement, the Patient Global Impression Scale of ...
PTSD-checklist (PCL-5), anxiety (Hamilton Anxiety Rating Scale, HAM-A), depression (Montgomery-Asberg Depression Rating Scale, MADRS), Clinician Global Impression (CGI), Patient Global Impression (PGI),...
separate out non-medication aspects of patients' experiences.Conclusion We developed a brief PRO instrument, the Patient Global Impression of Benefit–Risk (PGI-BR), which can be applied across disease areas to assess patient views of benefit–risk of a new medicine in the clinical trial setting...
The Patient Global Impression of Severity (PGI‐S) and Patient Global Impression of Improvement served as anchors. Results A total of 2,850 patients with either EM (EVOLVE‐1: 851; EVOLVE‐2: 909) or CM (REGAIN: 1,090) were included. The Cronbach''s alpha estimates of internal ...
The Patient Global Impression of Severity (PGI-S) and Patient Global Impression of Improvement (PGI-I), as well as voiding diaries assessed response to treatment. RESULTS A total of 36 women received SN during the study and had a mean(SD) age of 61(15) years and body mass index of 31...
Known-groups validity was assessed between patient groups separated by Patient Global Impression of Severity (PGI-S; normal vs. mild/moderate/severe). Internal reliability was assessed using Cronbach's alpha. Test-retest reliability was assessed using intraclass correlation coefficients (ICCs).Results...