Alternatively, difficulty can be quantified using a scale based on several parameters.22 Difficult SGD use: Difficult or failed oxygenation and ventilation with an SGD may result from difficulties accessing the patient’s mouth or hypopharynx, achieving a seal,23 or ventilating the lungs. Difficult...
On the other hand, the FDA currently recommends the use of body surface area (BSA) with an exponent of 0.67 to scale doses across species for small molecule anti-cancer agents [277]. However, since BSA is not directly measured with allometric equations, and due to the existence of ...