While some beneficial and detrimental associations of archaea to host health have been reported, overall the role of archaea in health and disease is still under investigation [5]. To date, archaea have been associated with a few illnesses, primarily gastrointestinal disorders such as constipation [...
The purpose of this investigation was to determine if FSK administration had an effect on the various elements of the intracellular signaling pathways of protein synthesis. Ten (n = 10) healthy, young (21.6 ± 1.3yrs), non-obese (BMI = 25.5 ± 3.5kg/m ), recreationally active males were...
Several anti-inflammatory drugs have been tested for their potential of reducing atherosclerosis risk. Statins are a good example of anti-inflammatory drugs that reduce the effects of inflammatory cytokines. Recent studies have shown that statins, in addition to their lipid-lowering effects, exert inhi...
In conclusion, we present a conductive hydrogel-based local delivery of bifunctional drug cocktails, thereby serving as a potential solution to intracochlear therapy of bimodal auditory rehabilitation and diseases beyond. Keywords: conductive hydrogel; hair cell; hair cell regeneration; apoptosis; ...
The resulting suspension in water was frozen at −80 °C overnight and then the water was removed by freeze drying method using a lyophilizer (Labconco, Freezone Benchtop 2.5L, Kansas City, MO, USA). 2.2.3. Preparation of PETE and PP MPs Five disposable plastic water bottles made from ...
We also provide a discussion of how these PTMs likely interface with each other to respond to extracellular cues to appropriately modify PXR activity. Keywords: nuclear receptor; pregnane X receptor; xenobiotics; cell signaling; phosphorylation; SUMOylation; ubiquitination; acetylation; PARylation ...