(2005). Molecular and cellular pathways of neurodegeneration in motor neurone disease. J. Neurol. Neurosurg. Psychiatry 76, 1046-1057. doi: 10.1136/jnnp.2004.048652Shaw P.J. Molecular and cellular pathways of neurodegeneration in motor neurone disease. J Neurol Neurosurg Psychiat 2005; 76: 1046--...
Molecular and cellular pathways of neurodegeneration in motor neurone disease. Shaw PJ.Molecular and cellular pathways of neurodegeneration in motor neurone disease[J].J Neurol Neurosurg Psychiatry,2005,76:1046-1057... PJ Shaw - 《Journal of Neurology Neurosurgery & Psychiatry》 被引量: 0发表: 2005...
If the pathways responsible for the variation could be pharmacologically targeted, symptoms might be delayed for decades.Here we summarize recent work on disease-modifying pathways in neurodegeneration that will be presented as a symposium at the 36th Annual Meeting of the Society for Neuroscience. We...
Neurodegeneration refers to a heterogeneous group of brain disorders that progressively evolve. It has been increasingly appreciatedthat many neurodegenerative conditions overlap at multiple levels and therefore traditional clinicopathological correlationapproaches to better classify a disease have met with limited...
Ocular regression conceals adaptive progression of the visual system in a blind subterranean mammal THE mole rat, Spalax ehrenberghi, is an extreme example of natural visual degeneration in mammals: visual pathways are regressed and incomplete, and the ab... HM Cooper,M Herbin,E Nevo - 《Nature...
The molecular basis of neurodegeneration in multiple sclerosis Studies aimed to elucidate the pathogenesis of the disease and to find new therapeutic options for multiple sclerosis (MS) patients heavily rely on experim... Hans,Lassmann,Jack,... - 《Febs Letters》 被引量: 290发表: 2011年 Nuclear...
The roles of intracellular protein-degradation pathways in neurodegeneration. Many late-onset neurodegenerative diseases, including Parkinson's disease and Huntington's disease, are associated with the formation of intracellular aggr... Rubinsztein,C David - 《Nature》 被引量: 2916发表: 2006年 Distinct...
Neurodegeneration and Neuronal Migration Defect Caused by Disruption in Vesicle Transport鈾 : Ablation of Vacuole Protein Sorting 18 (Vps18) Gene Leads to ... None - 《Journal of Biological Chemistry》 被引量: 8发表: 2012年 Ablation of Vacuole Protein Sorting 18 (Vps18) Gene Leads to Neurodege...
on defective mitochondria, eliciting the translocation of PARKIN from the cytosol to mediate the clearance of damaged mitochondria via autophagy (mitophagy). ... Thomas,M.,Durcan,... - 《Genes & Development》 被引量: 116发表: 2015年 Exploring new pathways of neurodegeneration in ALS: The role...
The aim of the present study is to elucidate the neuronal pathways associated to NSAIDs causing a reduction of the risk and progression of Alzheimer's disease. The research was developed administering the active enantiomer of ibuprofen, dexibuprofen (DXI), in order to reduce associated gastric toxi...